Sam Baldwin

Tom Hanks

Annie Reed

Meg Ryan

Jonah Baldwin

Ross Malinger

Walter

Bill Pullman

Jonah Baldwin

Ross Mallinger

Suzy

Rita Wilson

Jay

Rob Reiner

Becky

Rosie O'Donnell

Jessica

Gaby Hoffman

Victoria

Barbara Garrick

Greg

Victor Garber

Maggie Abbott Baldwin

Carey Lowell

Rob

Tom Riis Farrell

Uncle Milton

Calvin Trillin

Barbara Reed

Le Clanche Du Rand

Claire Bennett

Dana Ivey

Cliff Reed

Kevin O'Morrison

Dennis Reed

David Hyde Pierce

Betsy Reed

Valerie Wright

Irene Reed

Frances Conroy

Harold Reed

Tom Tammi

Dr. Marcia Fieldstone

Caroline Aaron

Loretta

Linda Wallem

Harriet

LaTanya Richardson

Keith

Tom McGowan

Baltimore Waitress

Marguerite Schertle

Bob

Brian McConnachie

Wyatt

Steve Mellor

Jessica's Mother

Hannah Cox

Jessica's Father

Rich Hawkins

Tiffany Saleswoman

Diane Sokolow

Stewardess

Tamara Plank

Mailman

Matt Smith

Clarise

Amanda Maher

New York Taxi Dispatcher

Michael Badalucco

New York Taxi Dispatcher

Jeff Mazzola

Seattle Maitre D'

Victor Morris

Seattle Waiter

Philip Mihalski

Cynthia

Julie Janney

Maitre D'

Tony Zazula

Seattle Detective

Donald J. Lee Jr.

Nervous Woman on Airplane

Mary A. Kelly

Elevator Man

John Boylan

Elevator Man

Robert Livingston

Taxi Driver

Philip Levy

Valet

Butch Stevenson

Information Booth Man

Sidney Armus

Juliet Taylor*

Sarah Trigger