Oscar

Will Smith

Oscar

Fernando Tejero

Angie

María Adanez

Don Lino

Robert De Niro

Angie

Renée Zellweger

Sykes

Santiago Ramos

Don Feinberg (voice)

Peter Falk

Shrimp / Worm / Starfish #1 / Killer Whale #2 (voice)

David Soren

Lenny (voice)

Jack Black

Katie Courrent

Mercedes Milá

Lola

Natalia Verbeke

Lola (voice)

Angelina Jolie

Ernie (voice)

Ziggy Marley

Sykes (voice)

Martin Scorsese

Giuseppe / Great White #1 (voice)

Lenny Venito

Don Lindo

Pepe Sancho

Announcer (voice)

Mark Swift

Great White #2

Jimmy Madio

Frankie

Michael Imperioli

Crazy Joe (voice)

David P. Smith

Great White #5

Joe Siravo

Luca

Vincent Pastore

Bernie (voice)

Doug E. Doug

Messenger Fish / Tip Fish #2 (voice)

Steve Alterman

Tip Fish #1 / Great White #4 / Whale / Killer Whale #1 (voice)

Sean Bishop

Katie Current

Katie Couric

Vinny

James Madio

Taxi Fish (voice)

David Yanover

Prawn Shop Owner (voice)

Phil LaMarr

Mrs. Sanchez (voice)

Shelley Morrison

Missy (voice) (uncredited)

Missy Elliott

Christina (voice) (uncredited)

Christina Aguilera

Shortie #2 (voice)

Kamali Minter

Shortie #1 (voice)

Bobb'e J. Thompson

Pontrelli (voice)

Saverio Guerra

Shortie #3 (voice)

Emily Lyon Segan

Great White #3

Frank Vincent

Great White #5 (voice)

Joseph Siravo

Motown Turtle (voice)

Jenifer Lewis

Cashier / Oyster / Clown Whale (voice)

James Ryan

Whale Wash Co-Worker (voice)

Latifa Ouaou

Shorty 3

Seana Kofoed