Niles

Daniel Davis

Fran Fine Sheffield

Fran Drescher

Maxwell Sheffield

Charles Shaughnessy

Chastity Claire "C.C' Babcock

Lauren Lane

Maggie Sheffield

Nicholle Tom

Brighton Sheffield

Benjamin Salisbury

Grace Sheffield

Madeline Zima

Guest Star

Monica Seles

Guest Star

Alex Trebek

Guest Star

Eartha Kitt

Guest Star

Susan Segal

Guest Star

Jane Seymour

Guest Star

Rachel Chagal

Aunt Freida

Lainie Kazan

Sylvia Fine

Renee Taylor

Guest Star

Catherine Oxenberg

Guest Star

Peter Marc Jacobson

Guest Star

Milton Berle

Guest Star

Derek Webster

Guest Star

Burke Moses

Guest Star

Dr. Joyce Brothers

Guest Star

James DiStefano

Yetta Rosenberg

Ann Morgan Guilbert

Guest Star

Joe Lando

Guest Star

John Astin

Guest Star

Adrienne Brett

Val Toriello

Rachel Chagall

Guest Star

Michael McKean

Guest Star

Dean Tarrolly

Guest Star

John G. Bishop

Guest Star

Anthony Addabbo

Guest Star

Elizabeth Taylor

Guest Star

Allan Rich

Guest Star

Marilyn Cooper

Guest Star

Ian Buchanan

Guest Star

Philip Casnoff

Guest Star

Florence Griffith-Joyner

Guest Star

John LaMorta

Guest Star

Fran Montano

Guest Star

Shawn Phillips

Guest Star

Paolo Seganti

Guest Star

Marvin Hamlisch

Guest Star

Michael Bacall

Guest Star

Donna Dixon

Guest Star

Dina Merrill

Roger Clinton

Roger Clinton

Guest Star

Athena Stensland

Guest Star

Justin Jon Ross

Guest Star

David L. Lander

Guest Star

Gloria Gifford

Guest Star

Barbara Howard

Guest Star

Amanda Carlin

Guest Star

Kane Picoy

Guest Star

Milton James

Guest Star

Mark Cheat

Guest Star

Ron Greshner

Guest Star

Iakavos Korres

Guest Star

Rosie O'Donnell

Guest Star

Burt Bacharach

Guest Star

Harry Van Gorkum

Guest Star

John Davidson

Guest Star

Kevin Light

Guest Star

Manny Kleinmuntz

Guest Star

Sue Goodman

Guest Star

David Lowe

Guest Star

Joey Dente

The Chester

Chester Drescher

Guest Star

Steve Posner

Guest Star

Ron Recasner

Guest Star

Todd Oldham

Guest Star

David Starzyk

Guest Star

David Letterman

Guest Star

Lorna Luft

Dr. Reynolds

Nora Dunn

Guest Star

Bryan Kirkwood

Guest Star

Magda Harout

Guest Star

Philippe Bergeron

Guest Star

Merrick Deamon

Guest Star

Cyndi James Gossett

Guest Star

Amy Lerman

Guest Star

Zack Norman

Guest Star

Dorothy Lyman

Guest Star

Andrew Steel

Uncle Stanley / Morty Fine

Morty Drescher

Guest Star

Helen Verbilt

Guest Star

Philip Lehl

Sammy

Ray Charles

Michael

Andrew Levitas

Orderly / Policeman

Lawrence Mandley

Aunt Rose

Sylvia Drescher

Dottie / Bridal Shop Clerk

Dee Dee Rescher