Phillip J. Fry/Profesor Hubert Farnsworth/Dr. John Zoidberg

Billy West

Turanga Leela

Katey Sagal

Bender (voice)

John DiMaggio

Mom (voice)

Tress MacNeille

Amy Wong (voice)

Lauren Tom

Himself

Donovan

Morbo/George Washington's Head

Maurice LaMarche

Hermes Conrad (voice)

Phil LaMarr

Himself

Rich Little

Free Waterfall Junior (voice)

Phil Hendrie

Robot Santa Claus

John Goodman

Dwayne/Vet Jeffrey Grant

Dave Herman

Himself

Vice President Al Gore

Umbriel

Parker Posey

Stephen Hawking

Stephen Hawking

Himself

Conan O'Brien

Turanga Leela

Alejandra de la Rosa

LaBarbara Conrad (voice) / Jackie Anderson (voice)

Dawnn Lewis

Herself

Nichelle Nichols

Morgan Proctor

Nora Dunn

Philip J. Fry

Benjamín Rivera

Herself

Claudia Schiffer

Nibbler (voice) / Tardigrades (voice) / Nibbler

Frank Welker

Dixie

Pamela Anderson

Bob Barker

Bob Barker

Electronic Mother's Day Card

Nicole St. John

Himself

Gary Gygax

Bender

Cesar Soto Valenzuela

The Masked Unit/Abner Doubledeal

Tom Kenny

Mr. Moviefone

Russ Leatherman

Michelle / Rude Boy / Head Museum Feeder (voice)

Kath Soucie

Robot Devil (voice)

Dan Castellaneta

Leonard Nimoy's Head (Voice)

Leonard Nimoy

George Takei's Head (voice)

George Takei

Kwanzaabot (voice)

Coolio

Leo Wong (voice) / Scoop Chang (voice)

Feodor Chin

URL (voice) / Barbados Slim (voice) / (voice)

Kevin Michael Richardson