Homer Jay Simpson/Barney Gumble/Grampa Simpson/Mayor Joe Quimby/Krusty the Klown/Groundskeeper Willie

Dan Castellaneta

Marjorie Bouvier Simpson/ Patty Bouvier/Selma Bouvier/Grandma Jackie Bouvier

Julie Kavner

Bart Simpson/Nelson Muntz/Todd Flanders/Ralph Wiggum/Kearney

Nancy Cartwright

Lisa Marie Simpson

Yeardley Smith

Charles Montgomery Burns/Waylon Smithers/Principal Seymour Skinner/Ned Flanders/Otto Mann/Scratchy/Kent Brockman/Dr. Julius Hibbert/Reverend Timothy Lovejoy

Harry Shearer

Moe Szyslak/Apu Nahasapeemapetilon/Chief Clancy Wiggum/Dr. Nick Riviera

Hank Azaria

Rex Banner

Dave Thomas

Roger Meyers Jr.

Alex Rocco

Fox Mulder

David Duchovny

Dolph

Tress MacNeille

John

John Waters

Jacques (voice) / Hank Scorpio (voice) / Brad Goodman (voice)

Albert Brooks

Larry Burns

Rodney Dangerfield

Edna Krabappel (voice) / Crowd (voice) / Edna Krabappel

Marcia Wallace

Lucious Sweet

Paul Winfield

Mr. Sparkle

Sab Shimono

Sideshow Bob (voice)

Kelsey Grammer

Troy McClure (voice) / Lionel Hutz (voice) / Lionel Hutz

Phil Hartman

Coyote

Johnny Cash

Cecil Terwilliger

David Hyde Pierce

Bret 'The Hitman' Hart

Bret Hart

Milhouse Van Houten

Pamela Hayden

Factory Foreman

Gedde Watanabe

Maude Flanders (voice) / Helen Lovejoy (voice) / Luann Van Houten (voice)

Maggie Roswell

Dana Scully

Gillian Anderson

HImself

Michael Buffer

Himself

Leonard Nimoy

Tough Street Dog / Mean Zoo Animals (voice) / Lord Nibbler (voice)

Frank Welker

Dancing Woman 1

Karen Maruyama

Additional voices

Greg Berg

Voice

Russi Taylor

Dancing Woman 2

Denice Kumagai

People Singer

Sally Stevens

Fat Tony (voice) / Gordus Antonius (voice)

Joe Mantegna

Llewellyn Sinclair (voice) / Enrico Irritazio (voice) / Artie Ziff (voice)

Jon Lovitz

The Commandant

Willem Dafoe

Himself

Tim Conway

Additional Voices (voice) / (voice) / Garbage Man (voice)

Karl Wiedergott*

Frank Ormand

Jack Lemmon

Big Daddy

Gailard Sarian

Sarah - Elementary School Musical

Lea Michele

(voice) / Additional Voices (voice) / Laughing Crowd (voice)

Chris Edgerly

Dr. Hibbert (voice) / Narrator (voice) / Security Guard (voice)

Kevin Michael Richardson

Carl Carlson (voice) / Lou (voice) / Carl Carlson

Alex Désert

Martin Prince (voice) / Sherri / Terri (voice)

Grey DeLisle

Orson Welles (voice) / (voice) / City Inspector (voice)

Maurice LaMarche

Bernice Hibbert (voice) / (voice) / Bernice Hibbert

Dawnn Lewis

Hyman Krustofsky (voice)

Jackie Mason

Mona Simpson (voice)

Glenn Close

Kumiko Albertson (voice) / Truth-Anne (voice) / Band Student (voice)

Jenny Yokobori

Helen Lovejoy (voice) / Maude Flanders (voice) / Miss Hoover (voice)

Marcia Mitzman Gaven

Constance Harm (voice) / Judge Harm (voice)

Jane Kaczmarek

Janine Powell (voice) / Lewis Clark (voice) / Kindergartener (voice)

Kimberly Brooks

Lunchlady Doris (voice) / Ice cream lady (voice) / Lunchlady (voice)

Doris Grau

Minnesota Girl / Maria Dominguez / Paper Boy (voice)

Jo Ann Harris

Julio (voice) / Julio Franco (voice) / Audience

Tony Rodriguez

Manjula Nahasapeemapetilon (voice)

Jan Hooks

Rayshelle Peyton (voice)

Kerry Washington

Ms. Myles (voice) / Old Lady (voice) / Mrs. Butterworth (voice)

Valerie Harper

Howard K. Duff VIII (voice) / Don Bookner (voice) / Howard Duff (voice)

Stacy Keach

Murphy (voice) / Dana Gould (voice) / I.N.S. Agent (voice)

Dana Gould

Dr. Lionel Budgie (voice) / Clayton (voice) / Mason Fairbanks (voice)

Michael York

Bumblebee Man (voice) / Lisa's Student (voice) / Gambling Old Man (voice)

Eric Lopez

Stephen Hawking (voice)

Stephen Hawking

Sarah Wiggum (voice)

Megan Mullally

Wink - The Game Show Host (voice) / George Takei (voice) / Akira Kurosawa (voice)

George Takei

Victor Kleskow (voice) / Dr. Jessup (voice) / Tabloid Editor (voice)

J.K. Simmons

Director

Steven Dean Moore

Director

Mark Kirkland

Director

Neil Affleck

Director

Chuck Sheetz

Director

David Silverman

Director

Lauren MacMullan

Director

Dominic Polcino

Director

Swinton O. Scott III

Director

Rich Moore

Director

Raymond S. Persi

Director

Pete Michels

Director

Jennifer Moeller

Director

Mike B. Anderson

Director

Michael Polcino