Sheldon

Iain Armitage

Mary Cooper

Zoe Perry

George Sr.

Lance Barber

Connie Tucker

Annie Potts

Georgie

Montana Jordan

Missy

Raegan Revord

Sheldon Cooper (voice)

Jim Parsons

Jeff Difford

Matt Hobby

Brenda Sparks

Melissa Peterman

Sheryl Hutchins

Sarah Baker

John Sturgis

Wallace Shawn

Billy Sparks

Wyatt McClure

Dr. Goetsch

John Hartman

Ira

Richard Kind

Dale Ballard

Craig T. Nelson

Glenn

Chris Wylde

Phyllis

Jayne Taini

Gene Lundy

Jason Alexander

Fran

Kerry O'Malley

Grant Linkletter

Ed Begley Jr.

Officer Robin

Mary Grill

Paige Swanson

Mckenna Grace

Peg

Nancy Linehan Charles

Mr. Bustifer

Duane Shepard Sr.

Coach Wilkins

Doc Farrow

Tam Nguyen

Ryan Phuong

June

Reba McEntire

Nathan

Steve Burns

Clara

Patricia Belcher

Luann

Winifred Freedman

Linda Swanson

Andrea Anders

Mr. Bustifer

Duane Shepard Sr.

Meredith

Amanda Payton

Dr. Bowers

Ryan Stiles

Kenneth

Jim Beaver

Marcus

London Chesire

Mandy McAllister

Emily Osment

Dorothy

Maree Cheatham

Mrs. Krawcynski

Carol Mansell

Hubert Givens

Brian Stepanek

Caroline

J. Rene Pena

Stan

Kurt Scholler

Sam

Taylor Spreitler

Man in Crowd

David Futernick

Veronica Duncan

Isabel May

Keith

Nolan Bateman

Self

Cyndi Lauper

Mr. Stover

Dennis Cockrum

Ralph

Louie Anderson

Kimberly / Local Newscaster

Katherine Von Till

Jana Boggs

Ava Allan

Principal Petersen

Rex Linn

Derek

Nick Alvarez

Lisa

Kerri Medders

Victoria MacElroy

Valerie Mahaffey

Marcus

London Cheshire

Albert Einstein

Phil Hendrie

Pastor Dave

Doug Cox

Mrs. Ebner

Carlease Burke

Susan

Deb Hiett

Sally

Lyn Alicia Henderson

Nigel

Davey Johnson

Evelyn Ingram

Danielle Pinnock

Carol

Stacey Moseley

Richard Feynman

John Mariano

Jim

Gerald Downey

Nate

Ed Ackerman

Janice

Emily Berry

Lynette

Chelsea Rae Bernier

Clark

Miller Tai

Lorraine

Karen Constantine

Luke

Corwin Allard

Customer 1

Aaron D. Alexander

Abigail Baker

Caleigh Kilpatrick

Student

Magnus Chhan

Lorraine

Karen Constantine

Professor Proton

Bob Newhart

Croupier

Rich Grosso

Customer #1

Christian Benz Belnavis

Evan

Mac Jarman

Batman

Diedrich Bader

Edwin

Joe Howard

Patron

Nick Armstrong

Customer #2

Arriane Alexander

Umpire

L. Emille Thomas

Young Georgie

Parker James Logie

Thoth

David Fennoy

Linda Hagemeyer

Wendie Malick

Jeremy

Ian Ousley

Audrey McAllister

Rachel Bay Jones

Mr. Bustifer

Duane R. Shepard Sr.

Jim McAllister

Will Sasso

Wade

Grady Lee Richmond

Rob

Dan Byrd

Doc Farrow

Ryan Phuong

Herschel Sparks

Billy Gardell

Director

Howie Deutch

Director

Mark Cendrowski

Director

Chris Koch

Director

Alex Reid

Director

Michael Judd

Director

Lea Thompson

Director

Melissa Joan Hart

Director

Jaffar Mahmood