Stan Smith / Roger (voice)

Seth MacFarlane

Francine Smith

Wendy Schaal

Hayley Smith

Rachael MacFarlane

Steve Smith

Scott Grimes

Klaus

Dee Bradley Baker

Todd

Abraham Benrubi

Mahmood

Jeff Bennett

Kevin Brougham

Paul Adelstein

Terry Bates (voice) / (voice) / Sanders (voice)

Mike Barker

Margie

Leigh Allyn Baker

Therapist

Rob Corddry

Girl

Alex Breckenridge

Avery Bullock (voice) / Avery Bullock as B (voice) / Jeff Fischer (voice)

Patrick Stewart

Snot Lonstein (voice) / Snot Lonstein / Eli Weisel (voice)

Curtis Armstrong

Old Lady

Ellen Albertini Dow

A.J.

James DeBello

Guest Voice

Alex Borstein

Doctor/Lt. Thacker

Beau Bridges

Whiny Parishioner

Josh Groban

Woman From Child Protective Service

Adilah Barnes

Jeff Fischer (voice) / Kidnapper (voice) / Donnie Patterson (voice)

Jeff Fischer

Guest Voice

Neil Feinberg

Jackson (voice) / Jackson / Charlie (voice)

Mike Henry

Himself

David Faustino

Harland

William Fichtner

(voice) / Michelle (voice) / Woman (voice)

Paget Brewster

Nat Faxon

Robin Bartlett

Father Donovan (voice)

Martin Mull

Guest Voice

Jodi Long

Vince Chung (voice)

John Cho

Bill Publisherman

Bryan Cranston

Acl-Lou/Mr. Simms/Monkey

John Carroll Lynch

George W. Bush

Chris Cox

Hazmat Guy

Ralph Garman

Angelina Jolie

Odile Corso

Derek Jeter

Catero Colbert

Quacky

Jon Cryer

(voice) / Fat Kid (voice) / Palin's Aide (voice)

Eric Edwards

Police Officer (voice) / Zach / Man (voice)

David Herman

Officer Bays

Jason Lee

Woman/American Girl 1

Gina Gershon

Miles

Peter Facinelli

Evil Barry

Craig Ferguson

Himself

Bruce Boxleitner

Duper (voice)

Phill Lewis

(voice) / Dr. Grossbard / Senator #1 (voice)

Peter Mackenzie

Cop 1/Editor

Michael G. Hagerty

Kazim

Oded Fehr

Gary/Rick

Chris Klein

French Maid/Candy Striper Stripper

Zooey Deschanel

Timmy/Kids

Scott Menville

Dr. Dandliker

Stephen Colbert

Jack Smith (voice) / Trailer Narrator (voice) / Anti-Feminist Author (voice)

Daran Norris

Girl in Line

Dayna Devon

Joey

Seth Green

Trudy

Jennie Garth

Bob Memari

Ron Livingston

Lisa Silver

Carmen Electra

Mr. Beauregard

Leslie Jordan

Hiko Yoshida (voice) / Katie (voice)

Sandra Oh

Guest Voice

Juanita Jennings

(voice) / Tow Truck Driver (voice) / ER Doctor (voice)

Fred Tatasciore

Guest Voice

Nat Faxon

Leon / Brad (voice) / Carl (voice)

John DiMaggio

Bela Karolyi/Karl Rove

Dennis Predovic

Principal Lewis (voice) / Billy (voice) / Principal Lewis

Kevin Michael Richardson

Al Tuttle (voice) / Car Salesman (voice)

Richard Kind

Janice

Nicole Sullivan

Dr. Gupta

Laura Linney

Mysterious Man

Peter Lurie

Linda Memari

Megyn Price

Dark Haired Man/Medic

Ioan Gruffudd

Dana

Busy Philipps

Barry Robinson (voice) / Barry Robinson / Spike (voice)

Eddie Kaye Thomas

DelMonaco (voice) / Jake (voice) / White Francine (voice)

Andy Richter

Dan Vebber

Brian Posehn

Ali/Prince/Man

Brian George

Guest Voice

Brad Grunberg

Gretchen Grossbard

Sherry Weston

Limo Driver/Himself

Peter Scolari

Himself

Josh Homme

Jim

Elias Koteas

Lindsay Coolidge

Terri Rodriguez

Hector

Freddy Rodríguez

Singing Sergeant

Reno Wilson

Old Lady/Wendie Jo

Wendie Jo Sperber

Hilary

Natasha Melnick

Betsy White

Marley Shelton

Bruce

Matthew Lillard

Herself

Kate Jackson

Bartender/Mr. Perkins/Parishioner

James Patrick Stuart

Stripper

Sarah Silverman

Old Guy/Police Officer 3

Zuhair Haddad

Alien Man

Jon Ross

Buckle (voice) / (voice) / Santa Claus (voice)

Matt McKenna

Bobo/Limo Driver

John Torbett

Kristy

Molly Shannon

Dick Reynolds (voice) / Wilbur Kentucky (voice) / Dick

David Koechner

Doyle/Fusfeld

Robert Tinkler

Mr. Durbin

Jim Wise

Dick (voice) / Dick / Dentist's Father (voice)

Stephen Root

Kim

Tori Spelling

Toshi Yoshida (voice)

Daisuke Suzuki

(voice) / Leonard Zane (voice) / Judge (voice)

André Sogliuzzo

Mitch

Jeremy Sisto

Man 2/Announcer 4

Grant Heslov

Salima/Bahir

April Stewart

Housekeeper/Betty Sue

David Zuckerman

Whitney Houston

Debra Wilson

(voice) / Hospital Doctor (voice) / Ugly Stepsister #3 (voice)

Marissa Jaret Winokur

(voice) / Dawson Family Member (voice) / Fitzwilliam Darcy

Chris Diamantopoulos

(voice) / Old Woman (voice) / Mom

Jill Talley

(voice) / Student (voice) / Puppet Guy (voice)

Alex Cuthbertson

Jay Leno

Wally Wingert

(voice) / Mertz (voice) / Townsperson (voice)

Judah Miller

Esther Lonstein (voice) / Danuta (voice) / Commercial Wife (voice)

Nicole Shabtai

Memphis Stormfront (voice) / Bar Bro (voice) / Old Man (voice)

Andrew Daly

Kashi (voice) / Co-Worker (voice) / Sleep Apnea Research Scientist (voice)

Nic Wegener

(voice) / Reginald (voice) / Crisp's Henchman (voice)

Erik Durbin

Dr. Kalgary (voice) / (voice) / Doctor (voice)

Alan Tudyk

Parker (voice) / (voice) / Piano Player (voice)

Parker Deay

(voice) / Dr. Weitzman (voice) / Alien (voice)

Matt E. Mixer

James Garfield (voice) / Co-Worker (voice) / (voice)

Chris Parnell

(voice) / CIA Guy (voice) / Kidnapper (voice)

Jonathan Fener

Suze (voice) / Trish the Waitress (voice) / Hannah (voice)

June Diane Raphael

(voice) / Wayne Gretzky (voice) / Jerry Seinfeld (voice)

Josh Robert Thompson

(voice) / Joe Chandler (voice) / Ragi Baba Follower (voice)

Joe Chandler

Raymond (voice) / Police Dispatch (voice) / Trey (voice)

Thomas Lennon

Trish (voice) / Trish / Molly (voice)

Casey Wilson

Tom (voice) / (voice) / Rogu (voice)

Josh Fadem

(voice) / Student (voice) / Various (voice)

Matt Fusfeld

(voice) / Anti-Christ (voice) / The Slow Janitor (voice)

Murray Miller

Coach Cathy (voice) / Elizabeth Bennet (voice) / Woman Carrying Dog (voice)

Courtenay Taylor

Security Guard (voice) / (voice) / Island Sheriff (voice)

Gary Anthony Williams

Porno Director (voice) / Prison Guard (voice) / Bus Driver (voice)

Khary Payton

Co-Worker (voice) / Eric Jermesian III (voice) / Jo-Jo (voice)

Tom Kenny

Colby (voice) / Scotty (voice) / Sanjay Bhudapar (voice)

Amir Talai

(voice) / Kid with Adult Voice (voice) / Stadium Announcer (voice)

Maurice LaMarche

(voice) / Student (voice) / Townsperson (voice)

Jeff Kauffmann

(voice) / Successful Classmate (voice) / Dawson Family Member (voice)

Brian Boyle

Pete Krachowski (voice) / Amish Man (voice) / Elijah (voice)

Joe Lo Truglio

Craig Robinson (voice) / (voice) / Sub Hub Employee (voice)

Craig Robinson

(voice)

Erik Sommers

Buck (voice) / Dennis (voice) / Mr. Collins

Tom Hollander

Preacher (voice) / (voice) / Chicago Dave (voice)

Jon Daly

Betty Smith (voice) / Marylin Thacker (voice)

Swoosie Kurtz

Sky Crooner (voice) / Groom (voice)

Tommy Blacha

Mah Mah (voice) / Mah Mah Ling / Helen (voice)

Amy Hill

Esther Lonstein (voice)

Susie Essman

Butt Insurance Salesman (voice) / Jesus Christ (voice) / Mayor Woodside (voice)

Will Forte

Mother (voice) / Chief of Police (voice) / Timmy's Mom (voice)

Jane Lynch

Police Officer (voice) / Harvey Lissel (voice) / Coach Melonis (voice)

Rob Riggle

Huell Howser (voice) / Wolf Poacher (voice) / Lorne Mikeys (voice)

James Adomian

Doctor (voice) / Roy Family (voice) / Security Guard (voice)

John Viener

(voice) / Sub Hub Employee (voice) / Cowboy Hat Girl (voice)

Lauren Lapkus

Lonnie Bolmenferg (voice) / Big Buy Employee (voice) / Vance (voice)

Eric Edelstein

Artemis (voice) / Curly Neal (voice) / Exterminator (voice)

Phil LaMarr

(voice) / Fruit Cart Man (voice) / Columbian Villager (voice)

Ignacio Serricchio

Officer Caruso (voice) / Police Officer (voice) / Bashir Salahuddin

Bashir Salahuddin

Airport Security Guard (voice) / Radio Station Security Guard (voice) / Guy #1 (voice)

J.B. Smoove

Costgo Employee (voice) / Andy Dick (voice) / Dry Cleaner (voice)

Nick Kroll

(voice) / Additional Voices (voice) / Steve's impressions (voice)

Asa Taccone

Truck Driver (voice) / Gay Man (voice) / Mervyn (voice)

Brett Gelman

Nurse Margaret (voice) / Phyllis (voice) / Enuice (voice)

Laraine Newman

Sebastian Hub (voice) / Country Bumpkin (voice) / Columbian Villager (voice)

Carlos Alazraqui

Bonnie Sanders / Nurse (voice) / Scottie's Mom (voice)

Wendi McLendon-Covey

Cuban Soldier in Dream / Theodore (voice) / Police Officer (voice)

Jason Mantzoukas

Debbie (voice)

Lizzy Caplan

Sharri Rothberg (voice)

Lisa Edelstein

(voice)

Laura McCreary

Ray (voice)

Victor Raider-Wexler

Connie Robinson (voice) / Doctor (voice)

Jessica St. Clair

Lorraine (voice) / Patty LaBelle (voice) / Angel (voice)

Niecy Nash

(voice) / Henchman (voice) / CIA Guy (voice)

Kevin Durand

Rick Rod (voice) / Cinema Ticket Man (voice) / Candy Maker (voice)

Patton Oswalt

Coconut Vendor (voice) / Omar (voice) / Adoptive Father (voice)

Fred Savage

Courtney (voice) / O'Shamus McPherson (voice) / Wesley Snipes (voice)

J. Lee

(voice) / TRF Agent (voice) / Big Ed (voice)

Rob Huebel

(voice) / Boy (voice) / Camper (voice)

Max Charles

(voice) / Various (voice) / Carl

Steve Hely

Shoshanna (voice) / Pharmacist (voice) / Veterinarian (voice)

Michaela Watkins

Girl (voice) / Student (voice) / Larry's Wife (voice)

Dreama Walker

(voice) / Tex / Driver (voice)

John Ennis

Gina (voice) / Airport Terminal Announcer (voice) / The Babe (voice)

Heather Anne Campbell

Robert Wuhl (voice)

Robert Wuhl

Dr. Ray Petit (voice)

Ted Danson