Tommy Pickles
Elizabeth Daily
Chas Finster/Grandpa Boris
Michael Bell
Didi Pickles (voice)
Melanie Chartoff
Chuckie Finster (voice)
Christine Cavanaugh
Phil DeVille / Lil DeVille (voice)
Kath Soucie
Angelica Pickles (voice)
Cheryl Chase
Kimi Finster (voice)
Dionne Quan
Stewart `Stu' Pickles
Jack Riley
Dil Pickles / Timmy McNulty (voice)
Tara Strong
Phil/Lil
Kath Soucie*
Grandpa Lou Pickles (voice)
Joe Alaskey
Dr. Prescott/Metalitron/Marco
Gregg Berger
Lucy Carmichael
Lisa Dinkins
Hershowitz/Jury Foreman/Press
Dan Castellaneta
Baby Drew Pickles/Sticky
Pamela Adlon
Jonathan
Rene Auberjonois
Grandpa Lou Pickles
David Doyle
Hairdresser/Counselor
Henry Gibson
Big Kid
Dana Hill
Randy Carmichael
Ron Glass
Boris Kropotkin
Manuel Garcia Merino
Narrator
Tony Jay
Pat Sajak
Pat Sajak
Charlotte Pickles (voice)
Tress MacNeille
Susie Carmichael (voice)
Cree Summer
Dr. Hoagie Dooser
Scott Menville
Blocky/Svetlana the Spy
June Foray
Howard DeVille/Paul
Phil Proctor
Megan
Christa Rimmer
Bob/Soap Actor
Jim Turner
Phonograph Singer
Mark Mothersbaugh
Mr. Namby/Reporter
Neil Ross
Chuckie Finster (voice)
Nancy Cartwright
Taffy
Amanda Bynes
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Hadley Kay
—
Tony Jay
—
Ron Glass
—
Jeremy Piven