Prince Adam, aka He-Man
Chris Wood
Skeletor (voice)
Mark Hamill
Teela (voice) / Mercenary 2 (voice)
Sarah Michelle Gellar
Evil-Lyn (voice) / Old Hag / Majestra (voice)
Lena Headey
Duncan / Man-At-Arms (voice) / Hooded Pilgrim (voice)
Liam Cunningham
Beast Man (voice) / Pilgrim 2 / Pilgrim 3 (voice)
Kevin Michael Richardson
Sorceress (voice) / Eternian Woman (voice)
Susan Eisenberg
Cringer/Battle Cat
Stephen Root
King Randor/Trap Jaw
Diedrich Bader
Andra (voice)
Tiffany Smith
Orko
Griffin Newman
Tri-Klops (voice)
Henry Rollins
Moss Man (voice)
Alan Oppenheimer
Queen Marlena (voice)
Alicia Silverstone
Roboto
Justin Long
Stinkor
Jason Mewes
He-Ro
Phil LaMarr
Scare Glow
Tony Todd
Kuduk (voice) / Priestess (voice)
Cree Summer
Mer-Man (voice)
Kevin Conroy
Baby Teela / Savage He-Man (voice)
Dee Bradley Baker
Ileena
Harley Quinn Smith
Grayskull (voice)
Dennis Haysbert
Wundar (voice)
Jay Tavare
Fistro (voice)
Ralph Garman
Pigboy / Goatman (voice)
Kevin Smith
Clamp Champ (voice)
Method Man
Ram Man (voice)
Danny Trejo