Hank Venture/The Monarch

Christopher McCulloch

Dr. Girlfriend / Henchman 21 (voice)

Doc Hammer

Dean Venture

Michael Sinterniklaas

Dr. Venture (voice)

James Urbaniak

Brock Samson

Patrick Warburton

Dr. Orpheus (voice)

Steven Rattazzi

Triana Orpheus (voice) / Jeanie (Mrs. Tom) (voice) / Princess Tinglepants (voice)

Lisa Hammer

Sirena (voice) / Receptionist / Kate (voice)

Cristin Milioti

Dr. Jonas Venture (voice) / Dr. Jonas Venture / Additional Voices (voice)

Paul Boocock

Action Johnny (voice) / Resistance 1 (voice) / Plastic Surgeon (voice)

Brendon Small

The Alchemist (voice) / President Breyer (voice)

Dana Snyder

Professor Impossible (voice) / Professor Impossible / Phage (voice)

Bill Hader

General Treister (voice) / Scaramantula (voice)

Toby Huss

The Master (voice)

H. Jon Benjamin

Professor Impossible (voice)

Stephen Colbert

Captain Sunshine (voice)

Kevin Conroy

Mandalay (voice) / Jefferson Twilight (voice)

Charles Parnell

Wonderboy (voice)

Patton Oswalt

Brown Widow (voice)

Nathan Fillion

Lance Hale / Mrs. Z (voice)

Seth Green

Director

Christopher McCulloch

Director

Juno John Lee