Penny

Kaley Cuoco

Leonard Hofstadter

Johnny Galecki

Sheldon Cooper

Jim Parsons

Howard Wolowitz

Simon Helberg

Raj Koothrappali

Kunal Nayyar

Amy Farrah Fowler

Mayim Bialik

Officer Hackett

Julio Oscar Mechoso

Dr. Elizabeth Plimpton

Judy Greer

Dr. Catherine Millstone

Elizabeth Bogush

Professor Crawley

Lewis Black

Bethany

Molly Morgan

Mary Cooper

Laurie Metcalf

Venkatesh Koothrappali

Frank Maharajh

Todd

Zachary Abel

Wil Wheaton

Wil Wheaton

Dr. Beverly Hofstadter

Christine Baranski

Abby

Danica McKellar

Debbie Wolowitz (voice)

Carol Ann Susi

Sandy

Yeardley Smith

Dr. V.M. Koothrappali

Brian George

Barry Kripke

John Ross Bowie

Stan Lee

Stan Lee

Sarah

Sarah Buehler

Stuart Bloom

Kevin Sussman

Young Man

Artie O'Daly

Joyce Kim

Ally Maki

Bernadette Rostenkowski

Melissa Rauch

Denny

Jason Mesches

Leslie Winkle

Sara Gilbert

Professor Laughlin

Oliver Muirhead

Judge J. Kirby

Steve Paymer

Mrs. Koothrappali

Alice Amter

Glen

Kevin Brief

Skeeter

Andy Mackenzie

Martha

Jen Drohan

Maria

Elena Campbell-Martinez

Sebastian

Steven Yeun

Zack Johnson

Brian Thomas Smith

Katee Sackhoff

Katee Sackhoff

Mrs. Gunderson

Lauri Johnson

Louie

Ajgie Kirkland

Waiter

David Trice

Guard

Marcus Folmar

Ira Flatow

Ira Flatow

Announcer (voice) / Lecturer (voice) / Man V.O. (voice)

Ed Lieberman

Emily Sweeney

Laura Spencer

Bert Kibbler

Brian Posehn

President Siebert

Joshua Malina

Priya Koothrappali

Aarti Mann

Halley Wolowitz (voice)

Pamela Adlon

Anu

Rati Gupta

Lucy

Kate Micucci

Denise

Lauren Lapkus

Stephen Hawking

Stephen Hawking

Richard Williams

Dean Norris

Mike Rostenkowski

Casey Sander

Michael J. Massimino

Michael J. Massimino

Janine Davis

Regina King

Arthur Jeffries

Bob Newhart

Claire

Alessandra Torresani

Althea

Vernee Watson-Johnson

Eric Gablehauser

Mark Harelik

Wyatt Teller

Keith Carradine

Dimitri

Pasha D. Lychnikoff