Tommy Pickles

E.G. Daily

Ranger Margaret (voice)

Whoopi Goldberg

Chuckie Finster (voice)

Christine Cavanaugh

Phil DeVilleLil DeVille

Kath Soucie*

Phillip DeVille/Lillian DeVille/Betty DeVille

Kath Soucie

Ranger Frank (voice)

David Spade

Angelica Pickles

Cheryl Chase

Didi Pickles / Minka Kropotkin (voice)

Melanie Chartoff

Dilan "Dil" Pickles (voice)

Tara Strong

Stuart 'Stu' Pickles (voice)

Jack Riley

Susie Carmichael (voice)

Cree Summer

Grandpa Lou Pickles

Joe Alaskey

Charles 'Chaz' Finster Sr. / Grandpa Boris Kropotkin / Drew Pickles (voice)

Michael Bell

Howard DeVille/Igor

Philip Proctor

Rex Pester (voice)

Tim Curry

Charlotte Pickles

Tress MacNeille

Reptar Wagon (voice)

Busta Rhymes

Grandpa Lou Pickles (voice)

Joe Alaskey

Nancy Cartwright

Lucy Carmichael (voice)

Hattie Winston

Dionne Quan

Aunt Miriam (voice)

Andrea Martin

Dr. Lipschitz (voice)

Tony Jay

Serge (voice)

Abraham Benrubi

TV Announcer (voice)

Gregg Berger

Female Guest (voice)

Mary Gross

Kevin McBride

United Express Driver (voice)

Charlie Adler

Nurse (voice)

Edie McClurg

Air Crewman (voice)

Roger Clinton

Lt. Klavin (voice)

Margaret Cho

Newborn Baby (singing voice)

Iggy Pop

Newborn Baby (singing voice)

Louis Fresse

Newborn Baby (singing voice)

Lisa Loeb

Newborn Baby (singing voice)

Lenny Kravitz

Newborn Baby (singing voice)

Dawn Robinson

Newborn Baby (singing voice)

Lou Rawls

Newborn Baby (singing voice)

Kate Pierson

Reporter (voice)

Steven Zirnkilton

Newborn Baby (singing voice)

Cindy Wilson

Robin Groth

Newborn Baby (singing voice)

Gordon Gano

Angel Harper

Newborn Baby (singing voice)

Laurie Anderson

Newborn Baby (singing voice)

Malik Isaac Taylor

Newborn Baby (singing voice)

Fred Schneider

Newborn Baby (singing voice)

Jakob Dylan

Newborn Baby (singing voice)

Patti Smith

Newborn Baby (singing voice)

Beck

Spike / Monkeys

Frank Welker

Newborn Baby (Singing Voice)

Phife Dawg

Director

Norton Virgien*

Director

Igor Kovalyov