Homer Simpson / Abe Simpson / Barney Gumble

Dan Castellaneta

Marjorie Bouvier Simpson/Patty Bouvier/Selma Bouvier/Grandma Jackie Bouvier

Julie Kavner

Bartholomew Jo-Jo "Bart" Simpson/Nelson Muntz

Nancy Cartwright

Lisa Marie Simpson

Yeardley Smith

Martin Prince (voice) / Martin Prince / Sherri

Russi Taylor

Moe Szyslak/Apu Nahasapeemapetilon/Chief Clancy Wiggum/Dr. Nick Riviera

Hank Azaria

Charles Montgomery Burns/Waylon Smithers/Principal Seymour Skinner/Ned Flanders/Otto Mann/Scratchy/Kent Brockman/Reverend Timothy Lovejoy

Harry Shearer

Milhouse Van Houten (voice) / Milhouse (voice) / Milhouse Van Houten

Pamela Hayden

Dolph

Tress MacNeille

Self

Dick Van Dyke

Rayshelle Peyton (voice)

Kerry Washington

Persephone

Elizabeth Banks

Dr. Spivak

Amanda Seyfried

Elton John

Kipp Lennon

Maisie

Karen Gillan

Self

Taika Waititi

Annette

Rachel Bloom

Sideshow Bob (voice)

Kelsey Grammer

Rock-Skipping Announcer

Dan Patrick

DJ Crazy Times

Kyle Gordon

Self

Kara Swisher

Euro Cashier

Audrey Trullinger

Hubert Wong

Rosalie Chiang

Pa MacWeldon

David Tennant

Edna Krabappel (voice) / Crowd (voice) / Edna Krabappel

Marcia Wallace

Sarah Wiggum (voice)

Megan Mullally

Self

Kylie Jenner

Chester Arborday

Matt Berry

Dean Belichick

Ken Marino

Jimmy Fallon

Matthew Friend

Ms. Biljana Electonica

Chrissi Poland

Hamish

Paul Higgins

Maude Flanders (voice) / Luann Van Houten (voice) / Helen Lovejoy (voice)

Maggie Roswell

Self

Andrew Ross Sorkin

Self

Ken Burns

(voice) / Additional Voices (voice) / Laughing Crowd (voice)

Chris Edgerly

Additional Voices (voice) / (voice) / Zombie Nurse

Karl Wiedergott*

Self

Christiane Amanpour

Self

Peter Coyote

Self

Peter Jackson

Dr. Hibbert (voice) / (voice) / Narrator (voice)

Kevin Michael Richardson

Carl Carlson (voice) / Lou (voice) / Carl Carlson

Alex Désert

Martin Prince (voice) / Sherri / Terri (voice)

Grey DeLisle

Fat Tony (voice) / Fat Tony / Fat Tony's Former Father (voice)

Joe Mantegna

Troy McClure (voice) / Lionel Hutz (voice) / Lionel Hutz

Phil Hartman

Bernice Hibbert (voice) / (voice) / Court Bailiff (voice)

Dawnn Lewis

Orson Welles (voice) / (voice) / City Inspector (voice)

Maurice LaMarche

Artie Ziff (voice) / Llewellyn Sinclair (voice) / Enrico Irritazio (voice)

Jon Lovitz

Kumiko Albertson (voice) / Truth-Anne (voice) / (voice)

Jenny Yokobori

Lewis Clark (voice) / Janey Powell (voice) / Janine Powell (voice)

Kimberly Brooks

Mona Simpson (voice)

Glenn Close

Julio Franco (voice) / Julio (voice) / (voice)

Tony Rodriguez

Hyman Krustofsky (voice)

Jackie Mason

Jacques (voice) / Hank Scorpio (voice) / Slick Manager (voice)

Albert Brooks

Maude Flanders (voice) / Helen Lovejoy (voice) / Miss Hoover (voice)

Marcia Mitzman Gaven

Constance Harm (voice) / Judge Harm (voice) / Judge Constance Harm (voice)

Jane Kaczmarek

Milhouse Van Houten (voice)

Kelly Macleod

Lunchlady Doris (voice) / Ice cream lady (voice) / Shotgun Pete's Receptionist (voice)

Doris Grau

Weasel (voice) / Martin Prince / Photography Club Member #3

Jo Ann Harris

Manjula Nahasapeemapetilon (voice)

Jan Hooks

Mrs. Butterworth (voice) / Nurse (voice) / Ms. Myles (voice)

Valerie Harper

Bumblebee Man (voice) / (voice) / Gambling Old Man (voice)

Eric Lopez

Baboons (voice) / Santa's Little Helper / Mr. Teeny

Frank Welker

Howard K. Duff VIII (voice) / Don Bookner (voice) / Howard K. Duff VIII

Stacy Keach

Murphy (voice) / I.N.S. Agent (voice) / Dana Gould (voice)

Dana Gould

Dr. Lionel Budgie (voice) / Nigel (voice) / Mason Fairbanks (voice)

Michael York

Stephen Hawking (voice)

Stephen Hawking

Akira Kurosawa (voice) / George Takei (voice) / Wink - The Game Show Host (voice)

George Takei

Victor Kleskow (voice) / Dr. Jessup (voice) / JJ Gruff (voice)

J.K. Simmons

Axel (voice) / Bull (voice) / Balfalmagog (voice)

Jonathan Lipow