Dr. Andrew Brown

Treat Williams

Delia Brown

Vivien Cardone

Ephram Brown

Gregory Smith

Amy Abbott

Emily VanCamp

Irv Harper

John Beasley

Edna Abbott

Debra Mooney

Dr. Harold Abbott

Tom Amandes

Bright Abbott

Chris Pratt

Nina Feeney

Stephanie Niznik

Guest Star

Mike Erwin

Guest Star

Tim DeKay

Rose Abbott

Merrilyn Gann

Guest Star

Betty White

Guest Star

Paul Wasilewski

Marcia Cross

Guest Star

J.K. Simmons

Guest Star

James Earl Jones

Guest Star

Dylan Walsh

Guest Star

Beau Bridges

Madison Kellner

Sarah Lancaster

Kristen Bell

Guest Star

Douglas Smith

Sharon Hart

Nancy Everhard

Guest Star

Michael Flynn

Guest Star

Kirsten Nelson

Louise

Jan Broberg

Guest Star

Philip Baker Hall

Laynie Hart

Nora Zehetner

Brenda Baxworth

Lee Garlington

Sam Feeney

Ryan Armstrong

Brittany Clark

Whitney Lee

Reid Bardem

Justin Baldoni

New Lifeguard

Michael Coe

Mrs. Greeley

Anna McKeown

Anesthesiologist

Michelle Peterson

Sam Feeney / Sam Feeney (voice)

Ben Hammond

Nurse

Wendy Watabe Peterson

Assisting Surgeon

Phil Riesen

Page

Katie Millar

Bypass Technician

James Jamison

Amanda Hayes

Anne Heche

Kid

Austin Archer

Martha Thompson

Micaela Nelligan

Jake Hartman

Scott Wolf

Mr. Jensen

Gordon Johnson

Kyle Hunter

Steven R. McQueen

Arnie

Brooks Bedore

John Hayes

Jason Beghe

Susie Clark

Haley McCormick

Kayla

Valerie Welcker

Topher Cole

Lukas Behnken

Dr. Chao

Freda Foh Shen

Jay

Charlie Weber

Julia Brown

Brenda Strong

Student

Jonathan Rudy

Principal Ackerman

David Downs

Coach Austin / The Do-Gooder

Scott Christopher

Delia's Friend

Lorna Gabrielle Balfour