Donatello (voice)

Micah Abbey

Leonardo

David Kunze

Michelangelo (voice)

Shamon Brown Jr.

Donatello

Ben Hadad

Michelangelo

Jerome Weinert

Genghis Frog

Hannibal Buress

Leonardo (voice)

Nicolas Cantu

Raphael (voice)

Brady Noon

Leatherhead

Rose Byrne

Raphael

Nando Schmitz

April O'Neil

Ayo Edebiri

Splinter

Stefan Gossler

Cynthia Utrom (voice)

Maya Rudolph

Rocksteady

John Cena

April O'Neil

Gabrielle Pietermann

April O'Neil (voice)

Ayo Edibiri

Splinter

Jackie Chan

Baxter

Erich Räuker

Bebop (voice)

Seth Rogen

Superfly (voice)

Ice Cube

Bebop

Tobias Kluckert

Cynthia

Nilam Farooq

Wingnut

Natasia Demetriou

Genghis Frog

Asad Schwarz

Baxter Stockman (voice)

Giancarlo Esposito

Leatherhead

Ranja Bonalana

Ray Fillet (voice)

Post Malone

Mondo Gecko (voice)

Paul Rudd

Times Square Guy (voice)

Jimmy Donaldson*

Spider (voice)

Derek Wilson

Curious Goon (voice)

Lukas Williams

Bad Bernie (voice)

Michael Badalucco

Bald Bronson (voice)

Dempsey Pappion

Cab Driver (voice)

John Capodice

TV Anchor (voice)

Andia Winslow

News Anchor (voice)

Raechel Wong

Normal Nate (voice)

David Faustino

Toupee Tom / Police Officer (voice)

Danny Mastrogiorgio

Responding Police Officer / Military Advisor (voice)

Noel Gibson

Bossy Goon / Scumbug (voice)

Alex Hirsch

Short Sharon (voice)

Myra Owyang

Good Human (voice)

Kevin Eastman

Paycheck Goon / Chop Shop Boss / Ratatouille Guard (voice)

Michael Rianda

Man Who Thought a Giant Rat was a Big Cat but was a Rat (voice)

Bobby Wagner

Gecko Goon (voice)

Greg Levitan

Helpful Construction Worker (voice)

Illya Quinteros

Sign My Baby Mom (voice)

Natalie Canizares

Apologetic Goon (voice)

Kyler Spears

Man Who Loves Being Young and Free to Go Places (voice)

Jeff Rowe