Dr. Andrew Brown

Treat Williams

Delia Brown

Vivien Cardone

Ephram Brown

Gregory Smith

Amy Abbott

Emily VanCamp

Irv Harper

John Beasley

Edna Abbott

Debra Mooney

Bright Abbott

Chris Pratt

Dr. Harold Abbott

Tom Amandes

Nina Feeney

Stephanie Niznik

Rose Abbott

Merrilyn Gann

Brenda Baxworth

Lee Garlington

Guest Star

Charles Durning

Dr. Jake Hartman

Scott Wolf

Hannah Rogers

Sarah Drew

Louise

Jan Broberg

Madison Kellner

Sarah Lancaster

Guest Star

Tom Parker

Guest Star

Kelly Carlson

Guest Star

Nia Long

Guest Star

Steven R McQueen

Guest Star

Leslie Hope

Guest Star

Jayne Brook

Guest Star

Simon Rex

Guest Star

Brooke Nevin

Colin Hart

Mike Erwin

Reid Bardem

Justin Baldoni

Guest Star

Joseph Bologna

Guest Star

Keith David

Guest Star

Reggie Austin

Guest Star

Christopher Egan

Guest Star

Gina Ravera

Guest Star

Renée Taylor

Brittany Clark

Whitney Lee

Sharon Hart

Nancy Everhard

Thurman Revere

Steven Anderson

Sam Feeney / Sam Feeney (voice)

Ben Hammond

Laynie Hart

Nora Zehetner

Wally

Duane Stephens

Page

Katie Millar

Amanda Hayes

Anne Heche

Martha Thompson

Micaela Nelligan

Mr. Jensen

Gordon Johnson

James Hart

Michael Flynn

Sam Feeney

Ryan Armstrong

Arnie

Brooks Bedore

John Hayes

Jason Beghe

Susie Clark

Haley McCormick

Kayla

Valerie Welcker

Topher Cole

Lukas Behnken

Dr. Chao

Freda Foh Shen

Jay

Charlie Weber

Julia Brown

Brenda Strong

Student

Jonathan Rudy

Principal Ackerman

David Downs

Coach Austin / The Do-Gooder

Scott Christopher

Delia's Friend

Lorna Gabrielle Balfour