Homer Jay Simpson/Barney Gumble/Grampa Simpson/Mayor Joe Quimby/Krusty the Klown/Groundskeeper Willie

Dan Castellaneta

Marjorie Bouvier Simpson/ Patty Bouvier/Selma Bouvier/Grandma Jackie Bouvier

Julie Kavner

Bartholomew Jo-Jo "Bart" Simpson/Nelson Muntz

Nancy Cartwright

Lisa Marie Simpson

Yeardley Smith

Martin Prince (voice) / Martin Prince / Sherri

Russi Taylor

Moe Szyslak/Apu Nahasapeemapetilon/Chief Clancy Wiggum/Dr. Nick Riviera

Hank Azaria

Charles Montgomery Burns/Waylon Smithers/Principal Seymour Skinner/Ned Flanders/Otto Mann/Scratchy/Kent Brockman/Dr. Julius Hibbert/Reverend Timothy Lovejoy

Harry Shearer

Milhouse Van Houten (voice) / Milhouse (voice) / Milhouse Van Houten

Pamela Hayden

Dolph

Tress MacNeille

Himself

Jay Leno

Akira Kurosawa (voice) / Wink - The Game Show Host (voice) / Waiter (voice)

George Takei

Harper

Kristen Bell

Paul

Tom Scharpling

Conrad

Stephen Merchant

Mona Simpson (voice)

Glenn Close

Himself

Andrew Rannells

Shop clerk

Ben Schwartz

Carol Berrera

Sofía Vergara

Dr. Lionel Budgie (voice) / Nigel (voice) / Clayton (voice)

Michael York

Jay

Utkarsh Ambudkar

Lem

Nick Kroll

Candace/Hannah Horvath

Lena Dunham

Hettie

Kate McKinnon

Sideshow Bob (voice)

Kelsey Grammer

Himself

Yo-Yo Ma

Himself

David Copperfield

Himself

Alton Brown

Hettie (singing voice)

Natalie Maines

Quinn

Kaitlin Olson

Scrat

Chris Wedge

Llewellyn Sinclair (voice) / Artie Ziff (voice) / Enrico Irritazio (voice)

Jon Lovitz

Edna Krabappel (voice) / Crowd (voice) / Edna Krabappel

Marcia Wallace

Dr. Hibbert (voice) / Narrator (voice) / Jay G (voice)

Kevin Michael Richardson

Barry

Jon Wurster

Dickie

Blake Anderson

Candace's friend

Allison Williams

Maude Flanders (voice) / Luann Van Houten (voice) / Helen Lovejoy (voice)

Maggie Roswell

Candace's friend

Zosia Mamet

Tyler Boom

Bobby Moynihan

Pit Master

Edward James Olmos

(voice) / Additional Voices (voice) / Laughing Crowd (voice)

Chris Edgerly

Candace's friend

Jemima Kirke

Bob Boilen

Bob Boilen

Dr. Zilowitz

Laura Ingraham

Additional Voices (voice) / (voice) / Prisoners

Karl Wiedergott*

Christoph Jablonka

Carl Carlson (voice) / Lou (voice) / Carl Carlson

Alex Désert

Anke Engelke

Sandra Schwittau

Troy McClure (voice) / Lionel Hutz (voice) / Lionel Hutz

Phil Hartman

Fat Tony (voice) / Gordus Antonius (voice)

Joe Mantegna

Sabine Bohlmann

Martin Prince (voice) / Sherri / Terri (voice)

Grey DeLisle

Bernice Hibbert (voice) / (voice) / Cannabis Influencer (voice)

Dawnn Lewis

Orson Welles (voice) / (voice) / Chef Naziwa

Maurice LaMarche

Kumiko Albertson (voice) / Truth-Anne (voice) / Band Student (voice)

Jenny Yokobori

Hyman Krustofsky (voice)

Jackie Mason

Helen Lovejoy (voice) / Maude Flanders (voice) / Miss Hoover (voice)

Marcia Mitzman Gaven

Jacques (voice) / Hank Scorpio (voice) / Tab Spangler

Albert Brooks

Julio Franco (voice) / Julio (voice) / Audience

Tony Rodriguez

Constance Harm (voice) / Judge Harm (voice)

Jane Kaczmarek

Lewis Clark (voice) / Janine Powell (voice) / Kindergartener (voice)

Kimberly Brooks

Lunchlady Doris (voice) / Ice cream lady (voice) / Della (voice)

Doris Grau

Susan / Collette the Waitress (voice) / Weasel #2

Jo Ann Harris

Manjula Nahasapeemapetilon (voice)

Jan Hooks

Rayshelle Peyton (voice)

Kerry Washington

Backstage Mom (voice) / Mrs. Butterworth (voice) / Old Lady (voice)

Valerie Harper

Monkeys / Princess (voice) / Executive Vice-President (voice)

Frank Welker

Howard K. Duff VIII (voice) / Don Bookner (voice) / Howard Duff (voice)

Stacy Keach

Murphy (voice) / Dana Gould (voice) / I.N.S. Agent (voice)

Dana Gould

Bumblebee Man (voice) / Lisa's Student (voice) / Gambling Old Man (voice)

Eric Lopez

Stephen Hawking (voice)

Stephen Hawking

Sarah Wiggum (voice)

Megan Mullally

J. Jonah Jameson (voice) / Victor Kleskow (voice) / Tabloid Editor (voice)

J.K. Simmons