National Geographic Channel's first late-night talk show stars renowned astrophysicist Neil deGrasse Tyson and is based on his popular podcast of the same name. The TV series' hourlong episodes provide a unique opportunity, Tyson says, to show how culturally pervasive and entertaining science can be. Guests including President Jimmy Carter, director Christopher Nolan, astronaut Chris Hadfield, journalist Arianna Huffington, actor George Takei and writer Norman Lear talk about topics like space travel, extraterrestrial life, the big-bang theory, the future of Earth and the environment. By bridging the intersection between pop culture and science, Tyson hopes to inspire everyone to "keep looking up."