Vanessa

Morena Baccarin

Wade/Deadpool

Ryan Reynolds

Ajax

Ed Skrein

Angel Dust

Gina Carano

Weasel

T.J. Miller

Ellie Phimister / Negasonic Teenage Warhead

Brianna Hildebrand

Jeremy (Pizza Guy)

Style Dayne

Blind Al

Leslie Uggams

On-Set Colossus (uncredited)

Andre Tricoteux

Meghan Orlovsky

Taylor Hickson

Flight Deck Guard

Paul Lazenby

Colossus (voice)

Stefan Kapičić

Dopinder

Karan Soni

Recruiter

Jed Rees

No5 Orange Manager

Ben Wilkinson

Gavin Merchant

Kyle Cassie

Buck

Randal Reeder

Warlord

Michael Benyaer

David Cunningham

Hugh Scott

Teen Girl #1

Ayzee

Boothe

Isaac C. Singleton jr.

Teen Girl #2

Naika Toussaint

Arcade Ticket Taker

Justyn Shippelt

Oncologist

Donna Yamamoto

Chinatown Merchant

Cindy Piper

Boothe

Isaac C. Singleton

Whisper Girlfriend

Emily Haine

Whisper Boyfriend

Amir Aatash

Pool Hall Goon

Chad Riley

Fight Club Boss

Paul Belsito

Garbage Truck Driver

Darcey Johnson

Whisper Boyfriend

Aatash Amir

Super Soldier #1

Kyle Rideout

Super Soldier #2

Jason Day

Strip Club DJ

Stan Lee

Strip Club Worker

Rachel Shaw

Super Soldier #2

Jason William Day

Bob

Rob Hayter

Ten-year-old Boy (uncredited)

Sean Quan

Biker (uncredited)

Dan Zachary

Strip Club Worker

Rachel Sheen

Stripper (uncredited)

Victoria De Mare

Stripclub Pole Performer (uncredited)

Heather Ashley Chase

Waitress Kelly (uncredited)

Kayla Adams

Guadalajaran Mother (uncredited)

Olesia Shewchuk

Guadalajaran Nurse (uncredited)

Fabiola Colmenero

Thug #2 (uncredited)

John Dryden

Strip Club Spectator (uncredited)

David Hardware

Fight Club Spectator (uncredited)

Tony Chris Kazoleas

Liefeld (uncredited)

Rob Liefeld

Elderly Man (uncredited)

David Longworth

Soldier #1 (uncredited)

Michael Neumeyer

Thug #3 (uncredited)

Anthony J. Sacco

Biker in Strip Club (uncredited)

David Santana

Fight Club Spectator (uncredited)

Bronwyne Sloley