Homer Jay Simpson/Barney Gumble/Grampa Simpson/Mayor Joe Quimby/Krusty the Klown/Groundskeeper Willie

Dan Castellaneta

Marjorie Bouvier Simpson/Patty Bouvier/Selma Bouvier/Grandma Jackie Bouvier

Julie Kavner

Bartholomew Jo-Jo "Bart" Simpson/Nelson Muntz

Nancy Cartwright

Lisa Marie Simpson

Yeardley Smith

Martin Prince (voice) / Martin Prince / Sherri

Russi Taylor

Moe Szyslak/Apu Nahasapeemapetilon/Chief Clancy Wiggum/Dr. Nick Riviera

Hank Azaria

Charles Montgomery Burns/Waylon Smithers/Principal Seymour Skinner/Ned Flanders/Otto Mann/Scratchy/Kent Brockman/Reverend Timothy Lovejoy

Harry Shearer

Milhouse Van Houten (voice) / Milhouse (voice) / Milhouse Van Houten

Pamela Hayden

Dolph

Tress MacNeille

Gus

John Lithgow

Self

Tree Rollins

Janitor

Hugh Jackman

Marge's head voice

Kristen Bell

Norse Deity/Loki

Alan Cumming

Mona Simpson (voice)

Glenn Close

Seamus

Chris O'Dowd

Grayson

Beck Bennett

Theo

Kumail Nanjiani

Orion Hughes/Darius Hughes

Abel "The Weeknd" Tesfaye

Michael

Victor Garber

Monk

John Autry II

Self

Adam Schefter

Sheila

Krysten Ritter

Edna Krabappel (voice) / Crowd (voice) / Edna Krabappel

Marcia Wallace

Mike Wegman

Michael Rapaport

Kostas Becker

Brian Cox

himself

Robert Reich

Therapist #3

Rachel Bloom

Female Voice/Sasha

Sara Chase

Herself

Christine Baranski

Sports Anchor

Scott Hanson

Jessica

Edi Patterson

Young Woman

Grey Griffin

Maude Flanders (voice) / Helen Lovejoy (voice) / Luann Van Houten (voice)

Maggie Roswell

Himself

Christian Siriano

Barb

Cristin Milioti

Warburton Parker

John Mulaney

Fat Tony (voice) / Gordus Antonius (voice)

Joe Mantegna

(voice) / Additional Voices (voice) / Laughing Crowd (voice)

Chris Edgerly

Mav

Seth Green

Bill Cipher

Alex Hirsch

Colby

Paul F. Thompkins

Additional Voices (voice) / (voice) / Garbage Man (voice)

Karl Wiedergott*

Collette

Jessica Paré

Sheriff Flanders

Timothy Olyphant

Cousin Greg

Nicholas Braun

Self

Charli D'Amelio

Dr. Hibbert (voice) / Narrator (voice) / Security Guard (voice)

Kevin Michael Richardson

Carl Carlson (voice) / Lou (voice) / Carl Carlson

Alex Désert

Troy McClure (voice) / Lionel Hutz (voice) / Lionel Hutz

Phil Hartman

Sideshow Bob (voice)

Kelsey Grammer

Orson Welles (voice) / (voice) / City Inspector (voice)

Maurice LaMarche

Bernice Hibbert (voice) / (voice) / Bernice Hibbert

Dawnn Lewis

Llewellyn Sinclair (voice) / Enrico Irritazio (voice) / Artie Ziff (voice)

Jon Lovitz

Hyman Krustofsky (voice)

Jackie Mason

Kumiko Albertson (voice) / Truth-Anne (voice) / Band Student (voice)

Jenny Yokobori

Helen Lovejoy (voice) / Maude Flanders (voice) / Miss Hoover (voice)

Marcia Mitzman Gaven

Jacques (voice) / Hank Scorpio (voice) / Brad Goodman (voice)

Albert Brooks

Constance Harm (voice) / Judge Harm (voice)

Jane Kaczmarek

Janine Powell (voice) / Lewis Clark (voice) / Kindergartener (voice)

Kimberly Brooks

Lunchlady Doris (voice) / Ice cream lady (voice) / Lunchlady (voice)

Doris Grau

Minnesota Girl / Maria Dominguez / Paper Boy (voice)

Jo Ann Harris

Julio (voice) / Julio Franco (voice) / Audience

Tony Rodriguez

Manjula Nahasapeemapetilon (voice)

Jan Hooks

Rayshelle Peyton (voice)

Kerry Washington

Ms. Myles (voice) / Old Lady (voice) / Mrs. Butterworth (voice)

Valerie Harper

Tough Street Dog / Mean Zoo Animals (voice) / Lord Nibbler (voice)

Frank Welker

Howard K. Duff VIII (voice) / Don Bookner (voice) / Howard Duff (voice)

Stacy Keach

Murphy (voice) / Dana Gould (voice) / I.N.S. Agent (voice)

Dana Gould

Dr. Lionel Budgie (voice) / Clayton (voice) / Mason Fairbanks (voice)

Michael York

Bumblebee Man (voice) / Lisa's Student (voice) / Gambling Old Man (voice)

Eric Lopez

Stephen Hawking (voice)

Stephen Hawking

Sarah Wiggum (voice)

Megan Mullally

Wink - The Game Show Host (voice) / George Takei (voice) / Akira Kurosawa (voice)

George Takei

Victor Kleskow (voice) / Dr. Jessup (voice) / Tabloid Editor (voice)

J.K. Simmons

Director

Steven Dean Moore

Director

Mark Kirkland

Director

Matthew Nastuk

Director

Neil Affleck

Director

Chuck Sheetz

Director

David Silverman

Director

Lauren MacMullan

Director

Dominic Polcino

Director

Swinton O. Scott III

Director

Rich Moore

Director

Raymond S. Persi

Director

Pete Michels

Director

Jennifer Moeller

Director

Mike B. Anderson

Director

Michael Polcino