Penny

Kaley Cuoco

Leonard Hofstadter

Johnny Galecki

Sheldon Cooper

Jim Parsons

Howard Wolowitz

Simon Helberg

Raj Koothrappali

Kunal Nayyar

Althea

Vernee Watson

Dr. Eric Gablehauser

Mark Harelik

Debbie Wolowitz (voice)

Carol Ann Susi

Mike

Andrew Walker

Christy Vanderbilt

Brooke D'Orsay

Missy Cooper

Courtney Henggeler

Kurt

Brian Patrick Wade

Mary Cooper

Laurie Metcalf

Toby Loobenfeld

D.J. Qualls

Chinese Leonard

Talbott Lin

Lalita Gupta

Sarayu Rao

Leslie Winkle

Sara Gilbert

Chen

James Hong

Dr. V.M. Koothrappali

Brian George

Jan

Judith Moreland

Doug

Allen Nabors

Chinese Sheldon

Howard Chan

Patty

Rachel Cannon

Dennis Kim

Austin Lee

Cheryl

Erin Allin O'Reilly

Bernadette Rostenkowski

Melissa Rauch

Amy Farrah Fowler

Mayim Bialik

Dan

Ronald Hunter

Mrs. Koothrappali

Alice Amter

Dmitri

Adam Gregor

Instructor

Sherry Weston

Summer

Sierra Edwards

Professor Goldfarb

Joel Brooks

Vicki

Kimberly Kevon Williams

Stan

Chuck Carter

Stuart Bloom

Kevin Sussman

Woman

Sandra Marquez

Waitress

Treisa Gary

Emma

Emma Degerstedt

Roberta

Cynthia Holloway

Son

Sergio Enrique

Barry Kripke

John Ross Bowie

Emily Sweeney

Laura Spencer

Wil Wheaton

Wil Wheaton

Priya Koothrappali

Aarti Mann

Beverly Hofstadter

Christine Baranski

Bert Kibbler

Brian Posehn

President Siebert

Joshua Malina

Zack Johnson

Brian Thomas Smith

Halley Wolowitz (voice)

Pamela Adlon

Anu

Rati Gupta

Lucy

Kate Micucci

Denise

Lauren Lapkus

Stephen Hawking

Stephen Hawking

Richard Williams

Dean Norris

Mike Rostenkowski

Casey Sander

Michael J. Massimino

Michael J. Massimino

Janine Davis

Regina King

Arthur Jeffries

Bob Newhart

Claire

Alessandra Torresani

Announcer (voice) / Lecturer (voice) / Man V.O. (voice)

Ed Lieberman

Wyatt Teller

Keith Carradine

Dimitri

Pasha D. Lychnikoff