Leonard Hofstadter

Johnny Galecki

Sheldon Cooper

Jim Parsons

Penny

Kaley Cuoco

Rajesh Koothrappali

Kunal Nayyar

Debbie Wolowitz (voice)

Carol Ann Susi

Howard Wolowitz

Simon Helberg

Steven V. Silver

Mark Cendrowski

Summer Glau

Summer Glau

Stuart Bloom

Kevin Sussman

Leslie Winkle

Sara Gilbert

Mikayla

Jodi Lyn O'Keefe

Dr. Eric Gablehauser

Mark Harelik

Charlie Sheen

Charlie Sheen

Dr. Stephanie Barnett

Sara Rue

Dr. David Underhill

Michael Trucco

Eric

Travis Schuldt

Octavia

Octavia Spencer

Lee Aronsohn

Kurt

Brian Patrick Wade

Alicia

Valerie Azlynn

Ramona Nowitzki

Riki Lindhome

Bernadette Rostenkowski

Melissa Rauch

Analeigh Tipton

Analiegh Tipton

Dr. George Smoot

Dr. George Smoot

Dr. Beverly Hofstadter

Christine Baranski

Amy Farrah Fowler

Mayim Bialik

Dr. V.M. Koothrappali

Brian George

Barry Kripke

John Ross Bowie

Charlotte

Michael Hyatt

Blaine

Tyler Olson

Kathy O'Brien

Emily Happe

Maria

Elena Campbell-Martinez

Jeremy

Will Deutsch

Model

Samantha Potter

Chuck Lorre

Bob La Masney

Mildred

Jane Galloway Heitz

Mrs. Koothrappali

Alice Amter

Lourdes

Livia Treviño

Tom

Mark Hames

Kristy Cecil

Rebecca

Jade Zdanow

Bill Prady

Wil Wheaton

Wil Wheaton

Charlie McDaniel

Peter Chakos

Bert Kibbler

Brian Posehn

David Goetsch

President Siebert

Joshua Malina

Bruce Peterson

Zack Johnson

Brian Thomas Smith

Tim Doyle

Halley Wolowitz (voice)

Pamela Adlon

Steven Molaro

Anu

Rati Gupta

Brian Seagrave

Denise

Lauren Lapkus

Stephen Engel

Stephen Hawking

Stephen Hawking

Mona Garcea

Althea

Vernee Watson-Johnson

Jennifer Glickman

Richard Williams

Dean Norris

Eric Kaplan

Mike Rostenkowski

Casey Sander

Faye Oshima Belyeu

Michael J. Massimino

Michael J. Massimino

Mary T. Quigley

Janine Davis

Regina King

Richard Rosenstock

Arthur Jeffries

Bob Newhart

Claire

Alessandra Torresani

Announcer (voice) / Man / Man V.O. (voice)

Ed Lieberman

Aarti Mann

Wyatt Teller

Keith Carradine

Dimitri

Pasha D. Lychnikoff