Actress Rosanna Arquette, the granddaughter of actor Cliff Arquette (aka "Charley Weaver"), was born into a theatrical family; her father was a founding member of the Committee, an improvisational theater troupe. As a youth she moved often with her family. At age 17 she appeared on the Los Angeles stage in Metamorphosis. Her family settled in Virginia, where she worked in local theater where she was spotted by a casting director. She soon had much work in TV movies in the late '70s. She debuted onscreen in More American Graffitti (1979). Her breakthrough came with her portrayal of condemned murderer Gary Gilmore's girlfriend in the TV movie The Executioner's Song (1982), which earned her much praise. That success led to a lead role in John Sayles's Baby, It's You (1983). She gained her greatest fame in the hit film Desperately Seeking Susan (1985), co-starring Madonna. From there she has maintained a steady screen career, usually playing kooky, off-beat, spacey, slightly eccentric women. She is the sister of actress Patricia Arquette.