Dr. Dave Bowman

Keir Dullea

Dr. Frank Poole

Gary Lockwood

Dr. Heywood R. Floyd

William Sylvester

Moonwatcher

Daniel Richter

HAL 9000 (voice)

Douglas Rain

Dr. Andrei Smyslov

Leonard Rossiter

Dr. Ralph Halvorsen

Robert Beatty

Elena

Margaret Tyzack

Dr. Roy Michaels

Sean Sullivan

Richard Wood

Ape

Brian Hawley

Mission Controller (voice)

Frank W. Miller

Ape

Bob Wilyman

Astronaut

Bill Weston

Ape

Danny Grover

Aries-1B Lunar Shuttle Captain

Ed Bishop

Ape

Andy Wallace

Astronaut

Glenn Beck

Ape

David Fleetwood

Poole's Father

Alan Gifford

Ape

Joe Refalo

Poole's Mother

Ann Gillis

Aries-1B Stewardess

Edwina Carroll

Ape Attacked by Leopard

Terry Duggan

Ape

Darryl Paes

Stewardess

Penny Brahms

Ape

Peter Delmar

Stewardess

Heather Downham

Ape

Laurence Marchant

Astronaut

Mike Lovell

Ape

Jonathan Daw

Astronaut

John Ashley

Ape

Scott MacKee

Ape

Jimmy Bell

Ape

David Charkham

Simon Davis

Ape

John Jordan

Ape

Keith Denny

Tony Jackson

Ape

David Hines

Ape

Anthony Jackson

Floyd's Daughter

Vivian Kubrick

Mission Controller

Frank Miller

Ape Killed by Moon-Watcher

Richard Woods