Bartleby/Barry
Ben Affleck
Bethany Sloane
Linda Fiorentino
Loki/Larry
Matt Damon
Cardinal Ignatius
George Carlin
Serendipity
Salma Hayek
Jay
Jason Mewes
Rufus
Chris Rock
Metatron
Alan Rickman
Azrael
Jason Lee
Silent Bob
Kevin Smith
God
Alanis Morissette
John Doe Jersey
Bud Cort*
John Doe Jersey/God the Man
Bud Cort
Clinic Girl
Janeane Garofalo
Gun Salesman
Jeff Anderson
Grant Hicks
Brian O'Halloran
Kane
Dwight Ewell
Protestor #2
Walt Flanagan
Whitland
Mark Joy
Nun
Betty Aberlin
Smooching Seaman
Scott Mosier
Stygian Triplet
Barrett Hackney
Priest at St. Stephen's
Dan Etheridge
Stygian Triplet
Jared Pfennigwerth
Mrs. Reynolds
Nancy Bach
Stygian Triplet
Kitao Sakurai
Bus Station Attendant
Guinevere Turner
Nun
Betty Amberlin
Protestor No. 1
Bryan Johnson
Gangster #1
Benjamin Cain
Protestor No. 2
Walter Flanagan
Waiter
Armando Rodriguez
Governor Dalton
Nancy Mosser
Gangster No. 2
Richard Baderinwa
Norman (Voice)
Ethan Suplee
Gangster No. 3
Javon Johnson
Gangster No. 4
Derrick Sanders
Blanket Boy on Train
Jon Gordon
Bartender
Matthew Maher
Officer McGee
Robert 'Ratface' Holtzman
Clinic Girl
Marie Elena O'Brien
Seaman Smoocher
Monica Hampton
Gangster #1
Benjamin J. Cain Jr.