Grandpa

Christopher Lloyd

Nat (voice)

Trevor Gagnon

Yegor (voice)

Tim Curry

Amos

Jürgen Kluckert

I.Q. (voice)

Philip Daniel Bolden

Nat's mom

Kelly Ripa

Louie (voice)

Robert Patrick

I.Q.

Henry Engels

Nadia (voice)

Nicollette Sheridan

Scooter (voice)

David Gore

Nadia

Nana Spier

Nat

Maximilian Belle

Nats Mutter

Arianne Borbach

Scooter

Dominik von Seydlitz

Poopchev (voice)

Ed Begley Jr.

Yegor

Thomas Albus

Cam Clarke

Scooters Mom (voice)

Adrienne Barbeau

IQ's mom

Mimi Maynard

Scott Manville

Buzz Aldrin

Buzz Aldrin

Commander Aldrin

Eddie Frierson

Commander Armstrong (voice)

Sandy Simpson

Commander Collins

David Cowgill

Leonide

Steven Kramer

Katie (voice)

Sophie Simpson

Pale Russian Fly (voice)

Grant George

Leonid

Steve Kramer

Senior Official (voice)

Phil Proctor

Mission Control 1969 (voice)

Lloyd Sherr

Fly Buddy #1 (voice)

Nicholas Guest

Fly Buddy #2

Archie Hahn

Fly at Launch (voice)

Lynnanne Zager

Butch (voice)

Scott Menville

American Newscaster (voice)

Michael McConnohie

Russian Newscaster (voice)

Doug Stone

Maggot #1 (voice)

Jessica Gee-George

Maggot #2 (voice)

Mona Marshall

Maggot #1 (voice)

Jessica Gee

Maggot #3 (voice)

Barbara Goodson

Pale Russian Fly (voice)

Gregg Berger

Additional Voices (voice)

Dean Wein

Additional Voices (voice)

Melora Harte

Mom's Maggot (voice)

Max Burkholder