Commander Spencer Armacost

Johnny Depp

Jillian Armacost

Charlize Theron

Sherman Reese

Joe Morton

Nan

Clea Duvall

Natalie Streck

Donna Murphy

Captain Alex Streck

Nick Cassavetes

Dr. Patraba

Samantha Eggar

NASA Director

Gary Grubbs

Shelly McLaren

Blair Brown

Jackson McLaren

Tom Noonan

Jackson McLaren

Tom Noonan

Nurse

Dawn Landon

Allen Dodge

Tom O'Brien

Shelly Carter

Lucy Lin

Reporter

Conrad Bachmann

Pat Elliott

Michael Crider

Dr. Conlin

Rondi Reed

Twins

Cole Mitchell Sprouse

Calvin

Jacob Stein

Twins

Dylan Sprouse

Spencer's Doctor

Charles Lanyer

Wide Eyed Kid No. 1

Timothy Wicker

Doctor

Gary Carlos Cervantes

Excited Fourth Grader

Brian Johnson

Yuppie Shark

Seth Barrish

Dried Up Socialite

Ellen Lancaster

Paula

Sarah Dampf

Waiter

Julian Barnes

Woman

Priscilla Shanks

Second Woman

Jennifer Burry

Third Woman

Susan Cella

Fourth Woman

Linda Powell

Security Guard

Elston Ridgle

Maitre D'

Robert Sella

Reporter (Video)

Samantha Carpel

Doorman

Stephen Berger

Waiter at Party

Michael Luceri

Storage Facility Client

Ben Van Bergen

Screaming Girl

Lyndsey Danielle Bonomolo

Pilot

Edward Kerr

Taxi Driver

Lahai Fahnbulleh

Businessman (uncredited)

Carl Burrows

Mission Control (uncredited)

Buck Holland

Director

Clea Duvall

Director

Rand Ravich

Director

Johnny Depp

Director

Charlize Theron

Director

Joe Morton

Director

Donna Murphy