Ron Woodroof

Matthew McConaughey

Dr. Eve Saks

Jennifer Garner

Rayon

Jared Leto

David Wayne

Dallas Roberts

Dr. Sevard

Denis O'Hare

Tucker

Steve Zahn

Richard Barkley

Michael O'Neill

Dr. Vass

Griffin Dunne

T.J.

Kevin Rankin

Nurse Frazin

Donna DuPlantier

Denise

Deneen D. Tyler

Clint

J.D. Evermore

Denise

Deneen Tyler

Orderly

Ian Casselberry

Kelly

Noelle Wilcox

Sunny

Bradford Cox

Michael

Rick Espaillat

Foreman

Lawrence Turner

Freddie

Lucius Falick

Rayon's Father

James DuMont

Francine Suskind

Jane McNeill

Tucker's Father

Don Brady

Border Agent

Sean Boyd

Effeminate Man

Matthew Thompson

Judge

Tony Bentley

News Anchor

Rachel Wulff

Stripper

Neeona Neal

Mr. Yamata

Scott Takeda

Dr. Hiroshi

Joji Yoshida

FDA Customs Agent

Carl Palmer

Ian

Martin Covert

Rick Ferris

Jonathan Tabler

Rog

Douglas M. Griffin

Cop

David Lichtenstein

Quicksilver Cowboy

Craig Borten

David Wayne

Dallas Ryan

Martin Pensa

Gay Cowboy

Henry Frost

Rodeo Announcer

Arthur Smith