Dr. Elaine Keener (segments "This is Dr. Keener" and "Fantasies about Rebecca")

Glenn Close

Carol Faber

Cameron Diaz

Rebecca Waynon (segment "Fantasies About Rebecca")

Holly Hunter

Christine Taylor (segments "Goodnight Lilly

Calista Flockhart

Rose

Kathy Baker

Detective Kathy Faber (segment "Love Waits For Kathy")

Amy Brenneman

Lilly (segment "Goodnight Lilly

Valeria Golino

Robert (segment "Fantasies About Rebecca")

Gregory Hines

Walter (segments "Fantasies About Rebecca" and "Love Waits For Kathy")

Matt Craven

Sam

Miguel Sandoval

Debbie (segments "Fantasies About Rebecca" and "Love Waits For Kathy")

Roma Maffia

Jay (segment "Someone For Rose")

Noah Fleiss

Albert (segments "Someone For Rose" and "Love Waits For Kathy")

Danny Woodburn

Nancy (segment "Fantasies About Rebecca")

Penelope Allen

Carmen Alba

Elpidia Carrillo

Elaine's Mother (segment "This is Dr. Keener")

Irma St. Paule

June (segments "Love Waits For Kathy" and "Goodnight Lilly

Mika Boorem

Receptionist (segment "Fantasies About Rebecca")

Laura Leigh Hughes

Nurse

Juanita Jennings

Police Officer

Erik King

Director

Rodrigo Garcia