Paul (Nick Cannon) and three others are accepted as test subjects by the mysterious Dr. Phillips (Peter Stormare). Initially, they are asked only to work on a survey -- but things take a sudden, violent turn when one of the subjects is executed. It's soon revealed that the remaining participants' lives depend on how they respond to various situations. But as the subjects' desperation grows, Phillips' colleague, psychologist Emily (Chloë Sevigny), debates ending the sick test.