Cooper

Matthew McConaughey

Amelia Brand

Anne Hathaway

Professor Brand

Michael Caine

Murph

Jessica Chastain

Tom

Casey Affleck

TARS

Bill Irwin

Doyle

Wes Bentley

Getty

Topher Grace

Old Murph

Ellen Burstyn

Young Murph

Mackenzie Foy

Young Tom

Timothée Chalamet

Donald

John Lithgow

Romilly

David Gyasi

Dr. Mann

Matt Damon

CASE (voice)

Josh Stewart

Administrator

Elyes Gabel

Ms. Kelly

Collette Wolfe

Lois

Leah Cairns

Coop

Liam Dickinson

Principal

David Oyelowo

Farmer

Francis X. McCarthy

NASA Board Member

William Devane

Doctor

Jeff Hephner

Smith

Andrew Borba

Nurse Practitioner

Lena Georgas

NASA Inspector

Mark Casimir Dyniewicz

Scientist

Kristian VanderHeyden

Crew Chief

Russ Fega

Jenkins

Marlon Sanders

Construction boss (uncredited)

Alexander Michael Helisek

Nurse

Brooke Smith

Girl on Truck

Flora Nolan

NASA Scientist (uncredited)

Benjamin Hardy

Boy on Truck

Griffen Fraser

Scientist (uncredited)

Kristian Van der Heyden

Astronaut (uncredited)

Joseph Oliveira

Little Boy in the hospital (uncredited)

Rory Nolan