After surviving the horrors of the Holocaust, architect Simon Wiesenthal dedicated the rest of his life to hunting down Nazis who escaped prosecution after the war. This documentary details his life and his work with the American War Crimes Unit, which tracked down more than 1,000 Nazi war criminals with his help. In interviews, various world leaders and Wiesenthal's friends discuss the motivations for his work, and how he manages to succeed even when facing seemingly insurmountable odds.