Igor (voice)

John Cusack

Dr. Holzwurm (voice)

Myleene Klass

Scamper (voice)

Steve Buscemi

Dr. Holzwurm's Igor (voice)

Robin Walsh

Dr. Glickenstein

John Cleese

Jaclyn / Heidi (voice)

Jennifer Coolidge

King Malbert (voice)

Jay Leno

Dr. Herzschlag (voice)

Matt McKenna*

Carl Cristall (voice)

Arsenio Hall

Dr. Schadenfreude

Eddie Izzard

Brain

Sean Hayes

Eva (voice)

Molly Shannon

Dr. Schadenfreude's Igor

Christian Slater

Himself

James Lipton

Announcer / Royal Guard #2 (voice)

Jess Harnell

Blind Woman / Killiseum Fan #1 (voice)

Zoë Bright

Blind Orphan #1 (voice)

Sophia Eraklis

Blind Orphan #2 / Blind Orphan #4 (voice)

A. Cheron Hall

Blind Orphan #3 (voice)

Alexander Leondis

Blind Orphan #6 (voice)

Michael Leondis

Blind Orphan #7 (voice)

Nicole Leondis

Blind Orphan #5 (voice)

Juliana Leondis

Buzz Offmann (voice)

Paul Vogt

Blind Orphan #8 (voice)

Robin Tisserand

Kay Cole

Animals' vocal effects (voice) (uncredited)

Frank Welker

Andreas Fröhlich

Hans-Jürgen Dittberner

Stefan Krause

Stefan Fredrich

Rita Engelmann

Antje von der Ahe