Sherlock Holmes

Will Ferrell

Dr. Watson

John C. Reilly

Grace Hart

Rebecca Hall

Inspector Lestrade

Rob Brydon

Mrs. Martha Hudson

Kelly Macdonald

Gustav Klinger

Steve Coogan

Millicent

Lauren Lapkus

Professor James Moriarty

Ralph Fiennes

Mycroft

Hugh Laurie

Queen Victoria

Pam Ferris

Doxy

Noah Jupe

Brawn

Adam Scherr

PC Smalls

Kieran O'Brien

Flotsam

Bella Ramsey

Haybag

Colby Mulgrew

Sigmund Freud

Wolf Roth

Pickle

Scarlet Grace

Jonathan Nightingale

Bronson Webb

Mud Fog

Billy Jenkins

Judge Over

Michael Culkin

Lady Stepping

Clare Foster

Newsie Man

Willem Dalby

Lestrade's Wife

Jana Pérez

Mark Twain

Nathan Osgood

Albert Einstein

David Shackleton

Charlie Chaplin

Paul Cassidy

Officer

Gerard Monaco

British Soldier

Jorge Leon Martinez

Herbert

Jordan Long

Mrs. Nightingale

Jamie-Rose Monk

Manager Mr. Petrucka

James Eeles

Butler

Jason Thorpe

Waiter

Robert Cawsey

Tough Kid

Paddy Holland

Russian Merchant

Karl Farrer

Waiter

Stanley Eldridge

Harden-Young Sherlock Holmes

Hector Bateman

Telegraph Operator

Oliver Maltman

Hudson's Guard

David Stoller

White Star-Line Girl

Amelia O'Loughlin

Newschild

Jack Riley

Newschild

Lilly Aspell

Newsie Kid-Jimmy

Riley White

Newschild

Ethan Rouse

La'Moy-English Gentleman

Christian Wolf

Newschild

Ellie Rose Eames

Bridgette

Ella Bright

Titanic Ship Officer Liaison

Jamie Baughan

Titanic Guest

Helen Duff

Steve - Queen's Royal Guard

Adam Ward

Hangman

Jess Liaudin

Beefeater #1

Anthony M. Dawson

Weird Child Companion

Wesley Kent-Hargreaves

Drooling Man Companion

Daniel Fearn

Fitness Instructor

Joseph Macnab

Nobleman

Deepak Anand

Disorientated Man Companion

Darren Lake

Telly-Phone Assistant

Matthew DiLiello

Priest

Martin Bishop

Newsie Kid-Timmy

Lochlan White

Houdini

Ben Lee

Fight Fan #1

Michael Buffer

Courtroom Person 3

Benjamin Lok

Fight Fan #2

Bruce Buffer

Tough Kid 2

Tommy Surridge

Announcer

Russell Wilcox

Upper Class Gentleman #1

Shawn Dixon

Billy Zane

Billy Zane

Sherlock's Mother

Laura Stevely

Young Sherlock Holmes

Hector Bateman-Harden*

Young Watson

Codie-Lei Eastick

Mr. Algernon Barkworth

Phil Hodges

Tough Kid

Layla Rose Boyce

Jane

Sadie Newman

School Girl

Lindy Barrett

Seamus

Harry Baxendale

Doxy's Dad

Sonnyboy Skelton

Buckingham Palace Guest

Martyn Mayger

Headmaster

Kenneth Hadley

Teacher #1

Paul Bigley

Executioner

David Handley

Mrs. Frobisher

Sara Beasley

Teacher #2

Sue Maund

Docker

Mick Slaney

John

Paul T.T. Easter

Yeoman of the Guard

Craig Thomas Lambert

Instructing Solicitor

John Kinory

Drunk

Henrihs Ahmadejevs

One Man Band

Martin Bassindale

Victorian Gentleman

Anthony Richard Rowe

Queen Victoria's Grenadier Guard

Joey Grima

Street Urchin

Edward Olhausen

Hargreaves-The Weird Child

Wesley Kent

Screaming Soldier

Neil Main

Phone Guy

David Bromley

Ringside Bookie

Mark Behan

Policeman

Angus Cook

Queens Footman

Samuel Dunning

Townsfolk

Anjan Kannan

Lady of the Night

Samantha Sharon Watson- Elizabeth

English Gentleman

Christian Wolf-La'Moy

Elizabeth - Lady of the Night

Samantha Sharon Watson

Rough Girl

Gintare Beinoraviciute

Director

Etan Cohen