Jack Shepard/Captain Zoom

Tim Allen

Marsha Holloway

Courteney Cox Arquette

Tucker Willams/Mega-Boy

Spencer Breslin

Dr. Grant

Chevy Chase

Summer Jones/Wonder

Kate Mara

Larraby

Rip Torn

Connor Shepard / Concussion

Kevin Zegers

Cindy Collins/Princess

Ryan Newman

Dylan West / Houdini

Michael Cassidy

Martial Arts Instructor

Tommy Chang

Cindy Collins / Princess

Ryan Whitney

Cindy's Mom

Cornelia Guest

Halloween Bully

Ashton Moio

Mean Bully

Ridge Canipe

Prince

Hunter Aarniokoski

Meaner Bully

Danny McCarthy

Dylan's Teacher

Thomas F. Wilson

Jupiter the Gas Giant

Rashad Richards

Wendy's Employee

David L. Lander

Reporter

Lauren Sanchez

Dick

Willie Garson

Reporter

Lauren Sánchez Bezos

Isolation Guard

Michael Anthony

Guard in Lecture Hall

John Carr Watson

Researcher Taylor

Jane Hajduk

Researcher

Zoe Doyle

Researcher Adam

Adam Bocknek

Large Agent

Tim Nasiopoulos

Gamma Room Technician

Darryl Flatman

Cheerleader No. 2

Deanna DeLisle

Researcher

Zoe Mugford

Cheerleader No. 1

Meg Anderson

Cheerleader No. 3

Kendra Rose Montagna

Scientist No. 1

Lenka Matuska

Scientist No. 2

David Farant

Corporal Lipscombe (uncredited)

Aaron Abrams

Carmen / Big haired Latina (uncredited)

Andrea Savo

Fat Swimmer (uncredited)

Nick Baga

Ace (uncredited)

Alexis Bledel

Cheerleader No. 4

Trisha Murray

Lab Researcher (uncredited)

Darryl Dinn

Girl with Big Hair (uncredited)

Allison Gordon

Kid In Pool (uncredited)

Sadey Paige Nifong