Jane Mason

Carole Lombard

John Horace Mason

James Stewart

Judge Joseph M. Doolittle

Charles Coburn

Mrs. Harriet Mason

Lucile Watson

Dr. Healy (uncredited)

Harry Davenport

Conway

Eddie Quillan

Sister Madeline

Alma Kruger

Eunice Doolittle

Ruth Weston

Annie (uncredited)

Esther Dale

Mr. Carter

Donald Briggs

Newark Radio Operator (uncredited)

Irving Bacon

Salt Lake City Hospital Chemist (uncredited)

Raymond Bailey

Lily (uncredited)

Louise Beavers

Hilda

Rene Orsell

Jim Hatton (uncredited)

Ward Bond

Judge (uncredited)

Harlan Briggs

Doolittle's Brother

Fred Fuller

Ranger on Telephone (uncredited)

Lane Chandler

Messerschmidt

Edwin Maxwell

Younger Doolittle (uncredited)

Frederick Chapin

Hutch

Harry Depp

Omaha Radio Operator (uncredited)

Russ Clark

Juror (uncredited)

Monte Collins

Office Boy (uncredited)

Mickey Rentschler

Co-Worker (uncredited)

James Conaty

Elevator Starter

Robert Emmett O'Connor

Sam

Milburn Stone

John, Jr., Newly Born

Bonnie Belle Barber

Mounted Policeman (uncredited)

Edgar Dearing

Doctor

Robert Strange

Airport Operations Manager (uncredited)

Robert Elliott

Doctor

Perry Ivins

Doctor

Gladden James

Farmer's Wife (uncredited)

Fern Emmett

Hospital Cashier (uncredited)

Betty Farrington

Johns Hopkins Technician (uncredited)

Mary Field

Rock Springs Radio Operator (uncredited)

Jack Mulhall

Denver Radio Operator (uncredited)

Garry Owen

Tipsy Blonde at New Year's Eve Party (uncredited)

Ruth Gillette

Radio Operator

Carlyle Moore Jr.

Collins (uncredited)

Russell Hopton

Farmer (uncredited)

Olin Howland

Radio Operator

Mike Kilian

Jury Foreman (uncredited)

Arthur Hoyt

Chicago Radio Operator (uncredited)

Victor Kilian Jr.

Radio Operator

Jack Austin

Radio Operator

Arthur Gardner

Ranger (uncredited)

Tom London

Nurse (uncredited)

Ethel Marical

Bailiff (uncredited)

Tom McGuire

Juror (uncredited)

James McNamara

Nurse (uncredited)

Wilhelmina Morris

Dr. Langham's Nurse-Receptionist (uncredited)

Nella Walker

Nurse (uncredited)

Marjorie Wood

Juror (uncredited)

John Picorri

Simon

Ivan Simpson

Office Worker (uncredited)

Cyril Ring

Farmer

Olin Howlin

John Horace Mason's Secretary (uncredited)

Mildred Shay

New York Hospital Chemist (uncredited)

Harry Worth

John Hopkin's Chemist

John Maurice Sullivan

John, Jr., at Age 1

Jackie Taylor