Craig

Keir Gilchrist

Bobby

Zach Galifianakis

Noelle

Emma Roberts

Dr. Eden Minerva

Viola Davis

Alyssa

Dana De Vestern

Lynn Gilner

Lauren Graham

George

Jim Gaffigan

Nia

Zoë Kravitz

Smitty

Jeremy Davies

Dr. Mahmoud

Aasif Mandvi

Nurse Harper

Karen Chilton

Muqtada

Bernard White

Aaron Fitzcarraldo

Thomas Mann

Ronny

Jared Goldstein

Scuggs

Alan Aisenberg

Humble

Matthew Maher

Johnny

Adrian Martinez

Alyssa Gilner

Dana DeVestern

Monica

Rosalyn Coleman

Jimmy

Lou Myers

Roger

MacIntyre Dixon

Solomon

Daniel London

The Professor

Novella Nelson

Mr. Reynolds

Leo Allen

Joanie

Morgan Murphy

Little Craig

Billy McFadden

Becca

Molly Hager

Jennifer

Ato Blankson-Wood

Science Geek

Caitlin Kinnunen

HS Director

Stephen Scott Scarpulla

HS Do-Gooder

Jee Young Han

Neil

Ben Folstein

Charlie

Stewart Steinberg

Roddy Skeaping

HS Teacher

Susan Blommaert

Bobby's Ex

Mary Birdsong

Acid Head

Ethan Herschenfeld

"Under Pressure" Nurse #2

Kenya Brome

"Under Pressure" Nurse #3

Delia Reed