Bruce

Masi Oka

Lloyd

Nate Torrence

Nina

Jayma Mays

Isabelle

Marika Dominczyk

Bob

Mitch Rouse

Neil

J.P. Manoux

Underchief / CIA Chief

Larry Miller

Howard

Bryan Callen

Judy

Kelly Karbacz

Matre D'

Terry Rhoads

Hymie

Patrick Warburton

Lab

Brian Gattas

El Presidente

Ruben Garfias

Steve Carell

Anne Hathaway

Upside Down Guy

Sunkrish Bala

Dwayne Johnson

Waitress

Erica Zodtner

Alan Arkin

Scientist

Winston J. Rocha

Terence Stamp

Young Isabella

Brianna Rain King

Agent 91

Terry Crews

C.I.A. Guy

Matt Kaminsky

David Koechner

Senior Guard

Al Coronel

Woman in Dress

Luisa Moraes

Bill Murray

Agent 34

Amanda Tosch

Ken Davitian

David S. Lee

Laboratory Worker #2

Ernie Grunwald

Dalip Singh

Laboratory Worker #3

Regan Burns

Geoffrey Pierson

Bill Romanowski

CIA Agent

Vincent M. Ward