Ben Thomas

Will Smith

Emily

Rosario Dawson

Ben's brother

Michael Ealy

Ezra Turner

Woody Harrelson

Dan

Barry Pepper

Connie Tepos

Elpidia Carrillo

Sarah Jenson

Robinne Lee

George Ristuccia

Bill Smitrovich

Larry

Joe Nunez

Stewart Goodman

Tim Kelleher

Susan

Sarah Jane Morris

Dr. Briar

Gina Hecht

George's doctor

Andy Milder

Connie's daughter

Madison Pettis

Young Ben

Connor Cruise

Holly Apelgren

Judyann Elder

Connie's son

Ivan Angulo

Kate/Home Health Care Nurse

Octavia Spencer*

Assisted Living Nurse

Cynthia Rube

Dan's Wife

Louisa Kendrick

Julie

Bojana Novaković

Inez

Fiona Hale

Neighbor Lady

Amanda Carlin

Nurse

Audrey Wasilewski

Woman in Diner

Charlene Amoia

Elevator Doctor

Rich Hutchman

St. Matthew's Volunteer

Dale Raoul

Bone Marrow Doctor

Steve Tom

Ben's OR Doctor

Rob Figueroa

Hospital Administrator

Kevin Cooney

Dialysis Nurse

Nadia Shazana

Neurosurgeon

Markus Flanagan

ER Doctor

Leif Rogers

Gabriele Muccino

Apogee engineer

Jack Yang