Zachry, et al

Tom Hanks

Captain Molyneux / Vyvyan Ayrs / Timothy Cavendish / Korean Musician / Prescient 2

Jim Broadbent

Luisa Rey, et al

Halle Berry

Adam Ewing / Poor Hotel Guest / Megan's Dad / Highlander / Hae-Joo Chang / Adam / Zachry Brother-in-Law

Jim Sturgess

Tilda/Megan's Mom/Mexican Woman/Sonmi-451/Sonmi-351/Sonmi Pr

Bae Doo-na

Nurse Noakes, et al

Hugo Weaving

Cabin Boy / Robert Frobisher / Store Clerk / Georgette / Tribesman

Ben Whishaw

Young Rufus Sixsmith/Old Rufus Sixsmith/Nurse James/Archivis

James D'Arcy

Talbot/Hotel Manager/Yoona-939/Rose

Xun Zhou

Autua / Lester Rey / Duophsyte

David Gyasi

Old Salty Dog/Mr. Meeks/Prescient 1

Robert Fyfe

Mr. Boerhaave/Guard/Leary the Healer

Alex Wuttke

Madame Horrox / Older Ursula / Yusouf Suleiman / Abbess

Susan Sarandon

Kona Chief, et al

Hugh Grant

Kupaka / Joe Napier / An-kor Apis / Prescient

Keith David

Young Cavendish

Robin Morrissey

Javier Gomez / Jonas / Zachry's Older Nephew

Brody Nicholas Lee

Enforcer

Ian van Temperley

Veronica

Amanda Walker

Ernie

Ralph Riach

Mrs. Hotchkiss

Tanja de Wendt

Mr. Boerhaave

Martin Wuttke

Little Girl With Orison at Papa Song's/Catkin/Zachry Relativ

Raeven Lee Hanan

Groundsman Withers

Götz Otto

Haskell Moore's Dinner Guest 2/Mozza Hoggins

Nial Fulton

Haskell Moore's Dinner Guest 3/Jarvis Hoggins

Louis Dempsey

Haskell Moore's Dinner Guest 4/Eddie Hoggins

Martin Docherty

Mr. Hotchkiss

Andrew Havill

Haskell Moore's Dinner Guest / Musician / Felix Finch / Lascivious Businessman

Alistair Petrie

Megan Sixsmith / 12th Star Clone

Zhu Zhu

Haskell Moore's Dinner Guest / Nurse Judd / Aide in Slaughtership

Sylvestra Le Touzel

Little Girl with Orison at Papa Song's / Catkin / Zachry Relative

Raevan Lee Hanan

Ursula's Mother / Herbalist

Dulcie Smart

Crane Operator

Gary McCormack

Haskell Moore's Dinner Guest / Mozza Hoggins

Niall Greig Fulton

Axwoman

Katy Karrenbauer

Union Spy

David Mitchell

Scan Enforcer

Marco Albrecht

Zachry Relative

Cody Lee

Papa Song Punk

Jojo Schoning

Young Ursula

Laura Vietzen

Ursula's Father

Thomas Kügel

Ursula's Daughter

Marie Ronnenbeck

Young Girl

Ruby Kastner

Ursula's Daughter

Marie Rönnebeck

Ursula's Granddaughter

Emma Werz

Miro

Mya-Lecia Naylor

Adam Grandson

Korbyn Hanan

Scientist / Executive

Anna Holmes

Adam Grandson

Korbyn Hawk Hanan

Porter

Moritz Berg

Zachry Relative

Gigi Lee

Zachry Relative

Genevien Lee

Mr. Roderick

Victor Esteban Sole

Secretary

Shaun Lawton

Lead Enforcer

Kristoffer Fuss

Ms. Judd Look-a-like

Heike Hanold-Lynch

Mr. Roderick

Victor Solé

Moore's Accountant / Finch's Friend (uncredited)

Jon Donahue