Charlotte

Julia Roberts

Fern

Dakota Fanning

Templeton

Steve Buscemi

Samuel

John Cleese

Gussy

Oprah Winfrey

Golly

Cedric the Entertainer

Bitsy

Kathy Bates

Betsy

Reba McEntire

Ike

Robert Redford

Brooks

Thomas Haden Church

Wilbur

Dominic Scott Kay

Narrator (voice)

Sam Shepard

Uncle

Abraham Benrubi

Elwyn the Crow (voice)

André Benjamin

Mr. Arable

Kevin Anderson

Avery

Louis Corbett

Homer Zuckerman

Gary Basaraba

Henry Fussy

Julian O'Donnell

Dr. Dorian

Beau Bridges

Mrs. Arable

Essie Davis

Mrs. Zuckerman

Siobhan Fallon Hogan

Teacher

Robyn Arthur

Lurvy

Nate Mooney

Minister

Nicholas Bell

Well Dressed Man

Teague Rook

Bystander

Julia Zemiro

New Teacher

Denise Kirby

Ball Thrower

Robert Plazek

Young Boy

Joseph Lotesto

Mayor

Michael Roland

Announcer

Don Bridges

Fair Official

Ian Watkin

Man at carnival

James Briggs

Boy at Fair

Peter Munson Hogan

Sheep Group (voice)

Joel McCrary

Sheep Group (voice)

Brian Stepanek

Sheep Group (voice)

Fred Tatasciore

Sheep Group (voice)

Bradley White

Aranea the Baby Spider (voice)

Jennessa Rose

Joy the Baby Spider (voice)

Maia Kirkpatrick

Nellie the Baby Spider

Briana Hodge

Jane Sibbett