Eve

Meg Ryan

Georgia

Diane Keaton

Maddy

Lisa Kudrow

Lou

Walter Matthau

Joe

Adam Arkin

Omar Kunundar

Duke Moosekian

Jesse Marks

Jesse James

Pat Mozell

Cloris Leachman

Ogmed Kunundar

Ann Bortolotti

Angie

Maree Cheatham

Dr. Kelly

Myndy Crist

Esther

Edie McClurg

Kim

Tracee Ellis Ross

Four Year Old Jesse

Ethan Dampf

Madge Turner

Celia Weston

Georgia's Assistant (Libby)

Libby Hudson

Victoria

Stephanie Ittleson

Nixon Library Representative

Bob Kirsh

Young Lou

Charles Matthau

Nurse At Mesh Window

Venessia Valentino

Six Year Old Eve

Paige Wolfe

Gay Man

R.A. Buck

Twelve Year Old Georgia

Katie Stratton

Gay Man

Phil Levesque

Four Year Old Maddy

Talia-Lynn Prairie

Young Pat

Kristina Dorn

Mother At Party

Mary Beth Pape

Doctor

Catherine Paolone

Woman Who Recognizes Maddy

Carol Mansell

Montana Dude

Lucky Vanous

Doctor On Soap

Bill Robinson

Sub-Editor

Jaffe Cohen

Hairdresser

Johnathan Cale

Event Attendee (uncredited)

Janet Dey