Marnie Minervini

Susan Sarandon

Emily

Lucy Punch

Mark

Michael McKean

Lori Minervini

Rose Byrne

Jacob

Jason Ritter

Zipper

J.K. Simmons

Elaine

Sarah Baker

Jillian

Cecily Strong

Freddy/Fredo

Jerrod Carmichael

Elise

Megalyn Echikunwoke

Old Woman

Jo Jordan

Dom

Lou Volpe

Trish

Casey Wilson

Angie

Irina Maleeva

Ben

Billy Magnussen

TV Daughter

Shiri Appleby

TV Dad

Harry Hamlin

TV Mom

Laura San Giacomo

Diane

Amy Landecker

Dani

Rebecca Drysdale

Officer Bernie

Marques Ray

Airport Security

Roger Aaron Brown

Officer Wells

Corey Reynolds

Nurse

Jae Suh Park

Kayla Emter

Tony

Tony Amendola

Cos

Robert Picardo

Tehya

Tehya Santos

Officer Lee

Randall Park

Officer Davis

Bill Fagerbakke

TV Director

Daniel Maurio

Tina

Beverly Mitchell

Pina

Despina Demetriou

Emily's Mom

Luanne Crawford