Ernesto Che Guevara

Benicio del Toro

Moises Guevara

Carlos Bardem

Aleida March

Catalina Sandino Moreno

Fidel Castro

Demián Bichir

Tania (Haydee Tamara Bunke Bider)

Franka Potente

Camillo Cienfuegos

Santiago Cabrera

President René Barrientos

Joaquim de Almeida

Celia Sanchez

Elvira Mínguez

Darío (David Ardiazola)

Óscar Jaenada

Pacho (Alberto Fernández Montes de Oca)

Pablo Durán

Ciro Algarañaz

Eduard Fernández

Raúl Castro

Rodrigo Santoro

Joaquin

Jorge Perugorría

Régis Debray

Marc-André Grondin

Ciro Redondo

Edgar Ramírez

Aleidita

María D. Sosa

Rogelio Acevedo

Victor Rasuk

Pombo (Harry Villegas Tamayo)

Othello Rensoli

Benigno

Armando Riesco

Tuma (Carlos Coello)

Norman Santiago

Urbano (Leonardo Tamayo Núñez)

Kahlil Méndez

Inti (Guido Peredo Liegue)

Cristian Mercado

Captain Mario Vargas

Jordi Mollà

Ciro Bustos

Gastón Pauls

Little Cowboy

Unax Ugalde

Loro (Jorge Vázquez Viaña)

Ezequiel Díaz

Alejandro Ramirez

Yul Vazquez

Rolando (Eliseo Reyes Rodriguez)

Rubén Ochandiano

Mario Monje

Lou Diamond Phillips

Antonio Domínguez Flores

Carlos Acosta-Milian

Lisa Howard

Julia Ormond

Miguel (Manuel Hernández Osorio)

Néstor Rodulfo

Vilma Espín

Marisé Álvarez

El Vallegrandino

Eduardo Espinosa

Lieutenant Carlos Fernández

Antonio de la Torre

George Roth

Mark Umbers

Captured Soldier #1

Raúl Arévalo

Fr. Schwartz

Matt Damon

Colonel Joaquín Zenteno

Pedro Casablanc

Bolivian Customs Agent #1

Raúl Beltrán

Ernesto (Freddie Maymura Hurtado)

Roberto Guilhon

Pedro (Antonio Jiménez Tardio)

Óscar Avilés

Aniceto Reinaga

Daniel Aguirre

Willy (Simón Cuba Saravia)

Diego Ortiz

Chapaco (Jaime Arana Campero)

Jorge Arturo Lora

Honorato Rojas

Luis Bredow

Daniel (Pastor Barrera Quintana)

Bart Santana

Vicente Roeabado Terrazas

Jesús Carrillo

Major Hernán Plata

Juan Carlos Vellido

Captured Soldier #2

Daniel Holguín

American #1

Tom Minder

Major Ralph 'Pappy' Shelton

James D. Dever

Captain Gary Prado

Roberto San Martín

Bolivian Interrogator

Luis Callejo

General Alfredo Ovando Candía

Tomás del Estal

Prado's Radio Operator

Miguel Antelo

Lieutenant Colonel Andrés Selich

David Selvas

Eduardo

Jesús Carroza

Bolivian Soldier

Martín Bello

Lieutenant Carlos Pérez

Enrique Arce

Sergeant Mario Terán

Cristhian Esquivel

Rudolfo (uncredited)

Benjamín Benítez

Embassy Girl (uncredited)

Mariu Bárcena

Ernesta Loud Demonstrator (uncredited)

Mizan Kirby

Un delegate (uncredited)

Jason Rivera

Indian Diplomat (uncredited)

Uzimann

News Cameraman (uncredited)

Steven Weisz