Sue Buttons
Allison Janney
Nancy
Mila Kunis
Detective Cam Harris
Regina Hall
Mina
Awkwafina
Rita
Wanda Sykes
Debbie
Ellen Barkin
Karl Buttons
Matthew Modine
Petey Buttons
Jimmi Simpson
Mr. Kim
Keong Sim
Gloria Michaels
Juliette Lewis
Ray
Clifton Collins Jr.
Jonelle
Samira Wiley
Leah Norton
Bridget Everett
Officer Jones
T.C. Matherne
Captain Riggins
Dominic Burgess
Steve
Chris Lowell
Jonathan Rose
Michael A. Newcomer
Robin Rose
Elizabeth Elkins
Donna/Make-Up Girl
Sylvia Grace Crim
Janet
Lucy Faust
Kentucky News Anchor
Shannon Cogan
Attractive Customer
Tate Taylor
Gloria's Assistant
Emily Russell
Bakery Clerk(as Cleta Ellington)
Cleta Elaine Ellington
Bank Manager
Deneen Tyler
Sweet Elderly Motel Clerk(as Susan Schwan McPhail)
Susan McPhail
Roberta
CC Castillo
Teenage Boy(as Zachary Shires)
Zack Shires
Becker
Sampley Barinaga
Additional Voices
Marcella Lentz-Pope