Leonard Chess
Adrien Brody
Etta James
Beyoncé Knowles
Muddy Waters
Jeffrey Wright
Revetta Chess
Emmanuelle Chriqui
Geneva
Gabrielle Union
Chuck Berry
Mos Def
Little Walter
Columbus Short
Willie Dixon
Cedric the Entertainer
Howlin' Wolf
Eamonn Walker
Revetta Chess
Emmanuelle Chriqui
Alan Freed
Eric Bogosian
James Cotton
Valence Thomas
Isabelle Allen
Tammy Blanchard
Mr. Feder
Jay O. Sanders
Chess Engineer
Norman Reedus
Phil Chess
Shiloh Fernandez
Manager
Aaron Munoz
Jimmy Rogers
Kevin Mambo
Robert
Jake Robards
Girlfriend
Chyna Layne
Hubert Sumlin
Albert Jones
Muddy Waters' Grandmother
Ginnie Randall
Maid
Osas Ighodaro
Muddy Waters' Girlfriend
Natasha Ononogbo
Pot Strong
Jordan Haynes
Minnie Ripperton
Suzette Gunn
Shelly Feder
Jill Flint
Little Walter's Girlfriend
Malikha Mallette
Harmonica Player
Rayan Lawrence
Charles Waters
Eshaya Draper
Lomax
Tony Bentley
Blonde Girl
Veronika Dash
Keith Richards
Marc Bonan*
Geneva's Teenage Son
Dexter Darden
Bouncer
Wade Mylius