Speckles the Mole (voice)

Nicolas Cage

Darwin the Guinea Pig (voice)

Sam Rockwell

Leonard Saber

Bill Nighy

Ben Kendall

Zach Galifianakis

Hurley the Guinea Pig (voice)

Jon Favreau

Blaster the Guinea Pig (voice)

Tracy Morgan

Juarez the Guinea Pig (voice)

Penélope Cruz

Bucky the Hamster (voice)

Steve Buscemi

Mooch the Fly (voice)

Dee Bradley Baker

Special Agent Kip Killian

Will Arnett

Marcie

Kelli Garner

Agent Carter

Gabriel Casseus

Agent Trigstad

Jack Conley

Connor

Tyler Patrick Jones

Jared the Skunk (voice)

Jared Lavette

Rosalita

Niecy Nash

Penny

Piper Mackenzie Harris

Micah the Fox (voice)

Micah Lavette

Grandpa Goodman

Loudon Wainwright III

Christa

Mini Anden

Terrell

Justin Mentell

FBI Director

Chris Ellis

Mouse

Hoyt Yeatman IV

Mice (voice)

Max Favreau

Agent

Troy Robinson

Agent

Travis Davis

Agent

Corey Michael Eubanks

Agent

James Huang

Agent

Steve Kelso

Skateboarder #1 (as Cameron Engels)

Camaron Engels

Agent

Eddie Yansick

Skateboarder #1

Cameron Engels

FBI Techie

Michael Papajohn

Traffic Cop

AlgeRita Lewis

Colf Course Exterminator

Bob Sherer

Falling Waitress

Jennifer England

Fireworks Tech

Jason Hellmann

SWAT Leader

Nicholas L. Teta

Andrzej Zielinski

Jaroslaw Boberek

Anna Przybylska

Arkadiusz Jakubik

Grzegorz Pawlak

Cezary Żak

Tomasz Steciuk