Astro Boy/Toby

Freddie Highmore

Dr. Tenma (voice)

Nicolas Cage

Widget

Madeline Carroll

Cora (voice)

Kristen Bell

Ham Egg

Nathan Lane

Orrin

Eugene Levy

General Stone (voice)

Donald Sutherland

Sparx

Matt Lucas

Dr. Elefun

Bill Nighy

Sludge (voice)

Sterling Beaumon

"Our Friends" Narrator

Charlize Theron

Zog (voice)

Samuel L. Jackson

Mr. Moustachio/Burning Robot (voice)

Ryan Stiles

Mr. Squirt / Math Cowboy / Boxer Robot

David Alan Grier

Mr. Squeegee / Scrapheap Head / Stinger Two

Alan Tudyk

Grace

Elle Fanning

Trashcan

Dee Bradley Baker

General Heckler (voice)

Newell Alexander

Stinger One

Bob Logan

Zane

Moisés Arias

Cora's Mom (voice)

Pilar Flynn

Mike the Fridge

David Bowers

The Little Stinker

Sofia Bowers

"Oh No!" Kid

Nicole Fletcher

Dr. Pigknuckle/Newscaster

Maryann Garger

Bride to Be

Tiffany Hillkurtz

Cowboy Robot

David Feiss

French Waiter Robot

Nicholas Guest

Billy

Max Burkholder

Sam

Victor Bonavida

Press Secretary

Steve Alterman

Metro City Sergeant

Rif Hutton

Metro City Girl

Madeleine Russell

Cora's Dad

Tony Matthews

Sludge

Sterling Beaumont

Director

David Bowers