Shake, Rattle & Rock follows the exploits of 1950s disenfranchised teens Susan (Renee Zellweger), Cookie (Patricia Childress), and Tony (Max Perlich) who find their calling when they start a hot rock & roll band at a time in America when rock was considered the devil's music. Despite the objections of Susan's prim mother (Nora Dunn) and the spinsterly town librarian (Mary Woronov), Tony opens a rock club and books for the club's big opening night his band, the Eggrolls, and the talented local vocal group the Sirens, led by the determined Sireena (Latanyia Baldwin). But the conservative forces mount against them, despite the efforts of leather-jacketed rebel Lucky (John Doe), and the club is closed at mid-performance, causing a riot in the small town. Will the forces of the Establishment win out, or is rock & roll here to stay?