When a mob mule carrying five million dollars in cold hard cash suddenly goes missing, the kingpin awaiting the substantial delivery discovers that he isn't the only one searching for the missing money in this quirky crime comedy starring Armand Assante, Steven Bauer, John Heard, Nicole Eggert, and Joe Piscopo. Tony Thick is a mobster who was expecting a lucrative visit from Los Angeles-based delivery man Lenny Long. But Lenny has failed to show, and now the impatient Mafioso suspects that the courier may have met with foul play. Hoping to find out the whereabouts of his cash as quickly as possible, Tony sends his henchman Shady to L.A. to recover the tidy sum. Little does Shady realize he's about to run into a whole cast of crazies who seem to be on the same mission. From Lenny's desperate wife to his scatterbrained mistress, his bodybuilding brother, and one seriously eccentric neurosurgeon, this exhausting money run seems to get more outlandish with each passing day.